Preprint Review Version 2 Preserved in Portico This version is not peer-reviewed

Liver Pathology as a Currently Health Problem

Version 1 : Received: 14 January 2022 / Approved: 17 January 2022 / Online: 17 January 2022 (12:37:22 CET)
Version 2 : Received: 20 July 2023 / Approved: 21 July 2023 / Online: 21 July 2023 (11:03:46 CEST)
Version 3 : Received: 31 July 2023 / Approved: 1 August 2023 / Online: 2 August 2023 (04:33:33 CEST)
Version 4 : Received: 18 October 2023 / Approved: 19 October 2023 / Online: 19 October 2023 (10:53:58 CEST)

How to cite: Chesca, A.E.; Medetova, A.; Abdulina, G.; Kabduova, A.; Beysembayeva, G.; Sandle, T. Liver Pathology as a Currently Health Problem. Preprints 2022, 2022010226. https://doi.org/10.20944/preprints202201.0226.v2 Chesca, A.E.; Medetova, A.; Abdulina, G.; Kabduova, A.; Beysembayeva, G.; Sandle, T. Liver Pathology as a Currently Health Problem. Preprints 2022, 2022010226. https://doi.org/10.20944/preprints202201.0226.v2

Abstract

Chronic liver diseases stimulate a degree of hepatocyte injury. This previously mentioned modifications, alters the known liver architecture and finally ends in cirrhosis. Liver pathology as cirrhosis develops after a long period of pathological alterations. The management of this liver pathology, is centred on the treatment of the causes and complications. Liver transplantation can be required in some cases. The aim of this article is to identify the best available evidences analyzing liver samples, normall and pathological. Normal liver with hepatocytes, Kiernann space, connective septa, observations using lens x10 and samples colored with Goldner Szekely trichrome stains. Beside, for comparisions, ill liver images, classic stain H&E. Inflammation is a great point that results in replacement of the healthy liver parenchyma with fibrotic tissue and regenerative nodules. In addition, progressive portal hypertension, systemic inflammation, and liver failure drive cirrhosis outcomes. All this previously mentioned factors, area great impact on the health-related quality of life of adult patients with liver cirrhosis. The management of this liver pathology, is centred on the treatment of the causes and complications. Liver transplantation can be required in some cases.

Keywords

liver; diseases; cirrhosis; diagnosis; management

Subject

Medicine and Pharmacology, Gastroenterology and Hepatology

Comments (1)

Comment 1
Received: 21 July 2023
Commenter: ANTONELLA CHESCA
Commenter's Conflict of Interests: Author
Comment: A new structure of paper
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