Version 1
: Received: 14 January 2022 / Approved: 17 January 2022 / Online: 17 January 2022 (12:37:22 CET)
Version 2
: Received: 20 July 2023 / Approved: 21 July 2023 / Online: 21 July 2023 (11:03:46 CEST)
Version 3
: Received: 31 July 2023 / Approved: 1 August 2023 / Online: 2 August 2023 (04:33:33 CEST)
Version 4
: Received: 18 October 2023 / Approved: 19 October 2023 / Online: 19 October 2023 (10:53:58 CEST)
How to cite:
Chesca, A.E.; Medetova, A.; Abdulina, G.; Kouchebekov, B.; Ahmetova, S.; Sandle, T. Laboratory Methods in the Screening of Viral C Hepatitis. Preprints2022, 2022010226. https://doi.org/10.20944/preprints202201.0226.v1
Chesca, A.E.; Medetova, A.; Abdulina, G.; Kouchebekov, B.; Ahmetova, S.; Sandle, T. Laboratory Methods in the Screening of Viral C Hepatitis. Preprints 2022, 2022010226. https://doi.org/10.20944/preprints202201.0226.v1
Chesca, A.E.; Medetova, A.; Abdulina, G.; Kouchebekov, B.; Ahmetova, S.; Sandle, T. Laboratory Methods in the Screening of Viral C Hepatitis. Preprints2022, 2022010226. https://doi.org/10.20944/preprints202201.0226.v1
APA Style
Chesca, A.E., Medetova, A., Abdulina, G., Kouchebekov, B., Ahmetova, S., & Sandle, T. (2022). Laboratory Methods in the Screening of Viral C Hepatitis. Preprints. https://doi.org/10.20944/preprints202201.0226.v1
Chicago/Turabian Style
Chesca, A.E., Saule Ahmetova and Tim Sandle. 2022 "Laboratory Methods in the Screening of Viral C Hepatitis" Preprints. https://doi.org/10.20944/preprints202201.0226.v1
Abstract
Objective: The study aimed to manage and to analyse the results of the laboratory tests, available nowadays, used from routine clinical practice, for screening of hepatitis C. Methods: comparison of ELISA method results (Enzyme-Linked Immunosorbent Assay) and chemiluminescence methods results. Beside previously mentioned, the study show the structural comparison of normal liver and pathologic liver with hepatic cirrhosis, using permanent samples colored after the technique protocol. Statistical analysis of this study results, was performed using the laboratory informatic system. Results: The results of the study are substantial and intricate. For this purpose, the results of preliminary EСL screening method of patients at risk for HCV who took part in the study, are presented in tables and figures. Results of this study are various and are correlate from different perspectives. Also good to mention that the correlations of results were used in order to identify a possible relationships between indicators of ELISA method and ECL index. More than, correlations antibodies detected in ECL and ELISA are point out. Conclusion: EСL and ELISA method results, are relevant for screening and for diagnostic confirmation in HCV risk patients. Unfotunately in the present study, were impossible to conclude about false-negative results. Good to know our opinion that RT-PCR technique, it is considered proper for the diagnosis of HCV.
Medicine and Pharmacology, Gastroenterology and Hepatology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
