Preprint Brief Report Version 1 This version is not peer-reviewed

A Flexible Genome-Scale Resource of SARS-CoV-2 Coding Sequence Clones

Version 1 : Received: 31 March 2020 / Approved: 2 April 2020 / Online: 2 April 2020 (04:15:54 CEST)
Version 2 : Received: 3 May 2020 / Approved: 4 May 2020 / Online: 4 May 2020 (18:28:01 CEST)

How to cite: Kim, D.; Knapp, J.J.; Kuang, D.; Cassonnet, P.; Samavarchi-Tehrani, P.; Abdouni, H.; Rayhan, A.; Sheykhkarimli, D.; Coyaud, E.; van der Werf, S.; Demeret, C.; Gingras, A.; Raught, B.; Jacob, Y.; Roth, F.P. A Flexible Genome-Scale Resource of SARS-CoV-2 Coding Sequence Clones. Preprints 2020, 2020040009 (doi: 10.20944/preprints202004.0009.v1). Kim, D.; Knapp, J.J.; Kuang, D.; Cassonnet, P.; Samavarchi-Tehrani, P.; Abdouni, H.; Rayhan, A.; Sheykhkarimli, D.; Coyaud, E.; van der Werf, S.; Demeret, C.; Gingras, A.; Raught, B.; Jacob, Y.; Roth, F.P. A Flexible Genome-Scale Resource of SARS-CoV-2 Coding Sequence Clones. Preprints 2020, 2020040009 (doi: 10.20944/preprints202004.0009.v1).

Abstract

The world is facing a major health crisis, the global pandemic of COVID-19 caused by the SARS-CoV-2 coronavirus, for which no approved antiviral agents or vaccines are currently available. Here we describe a collection of codon-optimized coding sequences for SARS-CoV-2 cloned into Gateway-compatible entry vectors, which enable rapid transfer into a variety of expression and tagging vectors. The collection is freely available via Addgene. We hope that widespread availability of this SARS-CoV-2 resource will enable many subsequent molecular studies to better understand the viral life cycle and how to block it.

Subject Areas

SARS-CoV-2; COVID-19; coronavirus; coding sequences; collections

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.