Version 1
: Received: 10 January 2019 / Approved: 11 January 2019 / Online: 11 January 2019 (15:51:51 CET)
How to cite:
Wong, T.; Tseng, Y.; Yeh, T.; Jhong, R.; Wang, Y.; Chang, H.; Cheng, P. The Complicated Body in Motion: Rediscovering the Mechanical Stimulations in Cell Models of Human Disease. Preprints2019, 2019010115. https://doi.org/10.20944/preprints201901.0115.v1
Wong, T.; Tseng, Y.; Yeh, T.; Jhong, R.; Wang, Y.; Chang, H.; Cheng, P. The Complicated Body in Motion: Rediscovering the Mechanical Stimulations in Cell Models of Human Disease. Preprints 2019, 2019010115. https://doi.org/10.20944/preprints201901.0115.v1
Wong, T.; Tseng, Y.; Yeh, T.; Jhong, R.; Wang, Y.; Chang, H.; Cheng, P. The Complicated Body in Motion: Rediscovering the Mechanical Stimulations in Cell Models of Human Disease. Preprints2019, 2019010115. https://doi.org/10.20944/preprints201901.0115.v1
APA Style
Wong, T., Tseng, Y., Yeh, T., Jhong, R., Wang, Y., Chang, H., & Cheng, P. (2019). The Complicated Body in Motion: Rediscovering the Mechanical Stimulations in Cell Models of Human Disease. Preprints. https://doi.org/10.20944/preprints201901.0115.v1
Chicago/Turabian Style
Wong, T., Hui-Yu Chang and Pei-Wen Cheng. 2019 "The Complicated Body in Motion: Rediscovering the Mechanical Stimulations in Cell Models of Human Disease" Preprints. https://doi.org/10.20944/preprints201901.0115.v1
Abstract
Thought runs through the mind like blood runs through our body to keep us alive. Like the mind, the body does not stay inert and is in constant motion. Not a single cell in our body is left inert unless cell is under stress or dying. These scenarios are reflected upon when a person is sick, the person lies in bed with less movement; however, is active when the person is healthy. The topic of mechanical stimulation has emerged due to the increasing understanding of the physical stimulations we face each day. Further understanding of the mechanically-regulated mechanism can help us explore the pathological events in a disease. Here, we reviewed the role of sensory proteins in pathological events that are observed in cardiomyopathy, cancer, respiratory, renal, obesity, genetics, physical injury and bacterial infection. Taken together, sensory proteins are mechanically-activated which assist reception of external physical stimulation and convert into biochemical to trigger intracellular signaling cascade.
Biology and Life Sciences, Biology and Biotechnology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
