COMMUNICATION | doi:10.20944/preprints202212.0070.v1
Subject: Life Sciences, Other Keywords: diester chlorogenoborate complex; green coffee bean; HPTLC/UV; HPTLC/ESI–MS; UHPLC/MS; FTIR
Online: 5 December 2022 (09:08:41 CET)
The natural compounds of boron have many applications, including as dietary supplement. Communication is based on the discovery that diester chlorogenoborate complex can be detected and quantified from green coffee bean. The study reports that such diester molecule can also be synthesized in stable form by direct reaction of boric acid and chlorogenic acid, in a mixture of acetonitrile–water (1:1, v/v), left to evaporate over a period of 48 hours, at room temperature, resulting a spirocyclic form (diester complex). The diester complex, with its molecular structure and digestibility attributes has potential application as prebiotic in gut health, oral health and as micronutrient essential for microbiota to human and animals.