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The Need to Look for Individual Differences in Meditators’ Neurophysiology

Submitted:

26 May 2026

Posted:

27 May 2026

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Abstract
Meditation is a practice that involves focusing the mind, typically with the aim of achieving a state of mental clarity, relaxation, and heightened awareness. This review delves into the question of why we need to look into individual differences in the neurophysiology of meditators. While the neuroscientific research conducted over the past 50 years has given us remarkable insights on what happens to the brain before, during, and after meditative practices, much of the research has focused on the “average” effects as seen in controls and meditators. However, the individual variations caused by cognitive abilities, personality traits, attention span, and emotional regulation skills have been understudied. Integrating neuroimaging research with psychology leads to the examination of how meditation influences brain activity and structure while highlighting individual differences in traits like neuroticism and mindfulness. The key motivation for this review lies in the fact that personality, attention, and cognitive mechanisms, among several other factors, are highly variable among individuals. The findings suggest that meditation has broader psychological, physiological, and neurological effects than previously thought, and underscores the need for further interdisciplinary research on its long-term and varying impact on mental health and well-being.
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Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
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