The classical scientific paradigm, centered on the ideal of a passive observer discovering pre-existing facts, is fundamentally challenged by insights from quantum mechanics and complex systems, where measurement is inherently interventional (Heisenberg, 1927; Barad, 2007). We propose the Ze System framework, a radical epistemological shift that redefines scientific inquiry as the active engineering of predictive conflicts to provoke latent reality into manifesting observable phenomena. The framework posits that a substantial portion of reality exists not as localized facts but as a high-entropy "wave" state of unactualized potentialities. By deploying competing, precise predictive models (e.g., P1 and P2 and applying a minimal, targeted intervention—the Ze probe (π)—this methodology forces a system into a crisis of choice. This forced localization is an entropic transaction: it expends energy, increases disorder, and irrevocably annihilates alternative potentials. Crucially, truth is not found in a model's confirmation but is forged in the structured, interpretable residual error (ϵL) that persists when a "greedy" model, equipped with a "cheating lever" to shape its own data, encounters an unyielding latent structure (L) (Tkemaladze, 2026). This paper details the ontological, methodological, and ethical foundations of this second-order science, framing Ze systems as entropy engines that strategically invest disorder to purchase certainty, thereby recasting the scientist's role from detached observer to accountable architect of co-created facts.