Submitted:
18 January 2026
Posted:
20 January 2026
You are already at the latest version
Abstract
Keywords:
1. Introduction
| Sr. | Personality Domains | Characteristics |
| 1 | Neuroticism | Anxiety, anger, depression, self-consciousness, immoderation, and vulnerability |
| 2 | Extraversion | Friendliness, gregariousness, assertiveness, activity level, excitement seeking, and cheerfulness |
| 3 | Openness | Imagination, artistic interests, emotionality, adventurousness, intellect, and liberalism |
| 4 | Agreeableness | Trust, morality, altruism, cooperation, modesty, and sympathy |
| 5 | Conscientiousness | Self-efficacy, orderliness, dutifulness, achievement striving, self-discipline, and cautiousness |
2. Materials and Methods
2.1. Research Design
2.1.1. Participants and Sampling Strategy
| Inclusion Criteria | Exclusion Criteria |
| A formal diagnosis of Substance Use Disorder as per the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (2013). | Presence of severe cognitive impairment or intellectual disability. |
| Proficiency in Urdu to comprehend the study instruments | Active psychosis or acute mania could compromise the validity of self-report measures. |
| Willingness to provide written informed consent. | Unwillingness to participate |
2.2. Measures
2.2.1. Data Collection
2.3. Data Analysis
3. Results
3.1. Latent Profile Analysis


- Profile 1 (Conscious-Warrior Personality Pattern) characterized by high neuroticism and conscientiousness, average extraversion and openness, and lower agreeableness.
- Profile 2 (Socially Expressive Personality Pattern) is distinguished by high extraversion, average neuroticism, openness, and conscientiousness, and lower agreeableness.
- Profile 3 (Highly Expressive and Emotionally Intense Personality Pattern) is marked by very high extraversion, high neuroticism and openness, average conscientiousness, and lower agreeableness.
- Profile 4 (Agreeable-Achiever Personality Pattern) is defined by high conscientiousness and extraversion, with average levels of neuroticism, openness, and agreeableness.
3.2. Post-Hoc Comparisons
3.3. Distinctiveness Latent Personality Profile
3.4. Validation of the Distinctiveness Personality Profile
4. Discussion
4.1. Discussion
4.2. Interpretation of the Latent Profiles
4.3. Validation of the Distinctiveness Latent Personality Profile
4.4. Limitations and Strength
4.5. Implications of the study
4.5.1. Theoretical Implications
4.5.2. Clinical and Practical Implications
4.5.3. Organizational and Educational Applications
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Conflicts of Interest
References
- American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed., text rev.; 2022. [Google Scholar] [CrossRef]
- Costa, P. T., Jr.; McCrae, R. R. Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI) professional manual. In Psychological Assessment Resources; 1992. [Google Scholar]
- Eysenck, H. J.; Eysenck, M. W. Personality and individual differences: A natural science approach; Plenum Press, 1997. [Google Scholar]
- Hawkins, J. D.; Catalano, R. F.; Miller, J. Y. Risk and protective factors for alcohol and other drug problems in adolescence and early adulthood: Implications for substance abuse prevention. Psychological Bulletin 1992, 112(1), 64–105. [Google Scholar] [CrossRef] [PubMed]
- Johnson, J. A. Measuring thirty facets of the Five Factor Model with a 120-item public domain inventory: Development of the IPIP-NEO-120. Journal of Research in Personality 2014, 51, 78–89. [Google Scholar] [CrossRef]
- Kendler, K. S.; Ohlsson, H.; Sundquist, J.; Sundquist, K. The rearing environment and risk for drug use: A Swedish national high-risk home-reared and adopted-away co-sibling control study. Psychological Medicine 2019, 49(12), 1995–2003. [Google Scholar] [CrossRef]
- Khan, A. A.; Hyder, S. Cultural considerations in the treatment of substance use disorders in Pakistan: A review. Journal of Pakistan Psychiatric Society 2020, 17(2), 45–52. [Google Scholar]
- Khan, I. A.; Khan, A.; Nazir, B.; Hussain, S. S.; Khan, F. G.; Khan, I. A. Urdu translation: The validation and reliability of the 120-item Big Five IPIP personality scale. Current Psychology 2019, 38(6), 1530–1541. [Google Scholar] [CrossRef]
- Khan, U.; Hyder, S. Substance use disorders in Pakistan: A scoping review. Journal of Substance Use 2020, 25(2), 115–122. [Google Scholar] [CrossRef]
- McCrae, R. R.; Costa, P. T., Jr. Personality in adulthood: A five-factor theory perspective, 2nd ed.; Guilford Press, 2003. [Google Scholar]
- Merz, E. L.; Roesch, S. C. Modeling trait and state heterogeneity using latent class analysis. In Handbook of structural equation modeling; Hoyle, R. H., Ed.; Guilford Press, 2012; pp. 549–563. [Google Scholar]
- Muthén, B.; Muthén, L. K. Integrating person-centered and variable-centered analyses: Growth mixture modeling with latent trajectory classes. Alcoholism: Clinical and Experimental Research 2000, 24(6), 882–891. [Google Scholar] [CrossRef] [PubMed]
- Nylund, K. L.; Asparouhov, T.; Muthén, B. O. Deciding on the number of classes in latent class analysis and growth mixture modeling: A Monte Carlo simulation study. Structural Equation Modeling: A Multidisciplinary Journal 2007, 14(4), 535–569. [Google Scholar] [CrossRef]
- Podsakoff, P. M.; MacKenzie, S. B.; Lee, J.-Y.; Podsakoff, N. P. Common method biases in behavioral research: A critical review of the literature and recommended remedies. Journal of Applied Psychology 2003, 88(5), 879–903. [Google Scholar] [CrossRef] [PubMed]
- Skewes, M. C.; Gonzalez, V. M. The biopsychosocial model of addiction. In Principles of addiction: Comprehensive addictive behaviors and disorders; Miller, P. M., Ed.; Academic Press, 2013; Vol. 1, pp. 61–70. [Google Scholar]
- Spurk, D.; Hirschi, A.; Wang, M.; Valero, D.; Kauffeld, S. Latent profile analysis: A review and “how to” guide of its application within vocational behavior research. Journal of Vocational Behavior 2020, 120, 103445. [Google Scholar] [CrossRef]
- Tein, J.-Y.; Coxe, S.; Cham, H. Statistical power to detect the correct number of classes in latent profile analysis. Structural Equation Modeling: A Multidisciplinary Journal 2013, 20(4), 640–657. [Google Scholar] [CrossRef] [PubMed]
- United Nations Office on Drugs and Crime. World Drug Report 2023; United Nations, 2023. [Google Scholar]
- Volkow, N. D.; Wise, R. A.; Baler, R. The dopamine motive system: Implications for drug and food addiction. Nature Reviews Neuroscience 2017, 18(12), 741–752. [Google Scholar] [CrossRef] [PubMed]
- Yin, X.; Zhao, W.; Zhou, R. A person-centered approach to personality and health: A systematic review. Health Psychology Review 2021, 15(2), 219–248. [Google Scholar] [CrossRef]
- Yin, Y.; Zhao, J.; Zhou, C. Personality and substance use: A review of recent research. Current Opinion in Psychology 2021, 38, 96–101. [Google Scholar] [CrossRef]
| Model | Classes | AIC | BIC | SABIC | Entropy |
| 1 | 2 | 19974 | 20043 | 19992 | 0.862 |
| 1 | 3 | 19677 | 19771 | 19701 | 0.923 |
| 1 | 4 | 19579 | 19698 | 19609 | 0.874 |
| 1 | 5 | 19561 | 19706 | 19598 | 0.872 |
| 3 | 2 | 19592 | 19703 | 19620 | 0.847 |
| 3 | 3 | 19461 | 19598 | 19496 | 0.846 |
| 3 | 4 | 19432 | 19594 | 19473 | 0.875 |
| 3 | 5 | 19431 | 19618 | 19478 | 0.855 |
| Profile 1 | Profile 2 | Profile 3 | Profile 4 | ||||||||
| Traits | M | SD | M | SD | M | SD | M | SD | F (3, 519) | p | η² |
| Neuroticism | 82.0 | 5.93 | 70.0 | 7.49 | 93.0 | 4.62 | 82.2 | 10.13 | 141.6 | < .001 | 0.5 |
| Extraversion | 89.1 | 10.02 | 82.8 | 11.44 | 100.4 | 6.15 | 93.5 | 6.95 | 114.2 | < .001 | 0.4 |
| Openness | 80.3 | 8.06 | 70.6 | 9.54 | 93.3 | 3.06 | 81.6 | 11.91 | 86.2 | < .001 | 0.4 |
| Agreeableness | 68.5 | 4.51 | 69.9 | 8.29 | 76.8 | 6.87 | 89.9 | 5.86 | 208.8 | < .001 | 0.6 |
| Conscientiousness | 91.4 | 5.17 | 74.0 | 5.30 | 84.3 | 3.70 | 97.2 | 6.63 | 507.7 | < .001 | 0.7 |
| Traits | Comparison (non-significant) | Profile Ranking |
| Neuroticism | Profile 1 vs 4 (p = 1.000) | 3 > 1 = 4 > 2 > 5 |
| Extraversion | All comparisons significant | 3 > 4 > 1 > 2 > 5 |
| Openness | Profile 1 vs 4 (p = 0.888) | 3 > 4 = 1 > 2 > 5 |
| Agreeableness | Profile 1 vs 2 (p = 0.589) | 4 > 3 > 2 = 1 > 5 |
| Conscientiousness | All comparisons significant | 4 > 1 > 3 > 2 > 5 |
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