Efficient placement of Virtual Machines (VMs) iscritical for optimizing resource utilization and ensuring servicereliability in cloud computing infrastructures. Existing validationmethods for VM placement algorithms, such as limited in-vivoexperiments and ad hoc simulators, often fail to reflect real-worldcomplexities and provide fair comparisons. This paper introducesVMPlaceS, a simulation framework built on SimGrid, designed toaddress these shortcomings by enabling the robust evaluation andcomparison of VM placement strategies. VMPlaceS facilitateslarge-scale scenario modeling with customizable parameters torepresent dynamic workloads and realistic platform conditions.By simulating centralized, hierarchical, and distributed algo-rithms, this study highlights the framework’s capability to assessscalability, reactivity, and SLA adherence in various deploymentscenarios. VMPlaceS emerges as a valuable tool for researchersand practitioners to explore innovative VM placement solutionsand advance the field of cloud computing resource management.