Submitted:
29 September 2025
Posted:
30 September 2025
You are already at the latest version
Abstract
Keywords:
Introduction
“Every individual thing is determined to exist and act by another cause, which is also determined by another, and so on to infinity.”1—Baruch de Spinoza
“No man ever steps into the same river twice.”2—Heraclitus of Ephesus
Evolution
“We see nothing of these slow changes in progress until the hand of time has marked their course.”—Charles Darwin
Biological Evolution
Universal Evolution
Relativity
Perturbation
Evaluation
Stabilization
Determination
Arrow of Evolution
Computation
“Evolution is an algorithmic, substrate-neutral, mindless process that nevertheless generates design.”—Daniel C. Dennett
What is Computation?
Consciousness
“Consciousness is not a chain, but a stream. It flows, bends, and merges — always changing, never still.”—William James
Einstein’s Relativity
Accessibility
“Accessible pathways tell the evolution where to flow, evolution tells pathways how to access.”—John Archibald Wheeler
Short-Term Memory
Working Memory
Spatial Contiguity and Reachability Constraints
Temporal Order and Proximity
Activations Histories
Associative Strength and Network Topology
Modulatory Factors
Environmental Entanglement
The Brain Is Not Only a Predictive Machine
Thought
Always, everything, everywhere, is and was optimized.
“This is the best of all possible worlds.”—Gottfried Wilhelm Leibniz
The Only World, the Only Way Evolution
Validity
Self
Acknowledgements
Conflict of Interest
| 1 | Baruch Spinoza, Ethics, trans. Edwin Curley (London: Penguin Classics, 1996), Part I, Proposition 28, 16. |
| 2 | Heraclitus, quoted in G. S. Kirk, J. E. Raven, and M. Schofield, The Presocratic Philosophers: A Critical History
with a Selection of Texts, 2nd ed. |
References
- 2003. Mutation and the genetic variation of populations. In: NEAL, D. (ed.) Introduction to Population Biology. Cambridge: Cambridge University Press.
- 2018. Relativity and Least Action. In: ROJO, A. & BLOCH, A. (eds.) The Principle of Least Action: History and Physics. Cambridge: Cambridge University Press.
- ABEN, B., STAPERT, S. & BLOKLAND, A. 2012. About the Distinction between Working Memory and Short-Term Memory. Front Psychol, 3, 301. [CrossRef]
- ADAMI, C., OFRIA, C. & COLLIER, T. C. 2000. Evolution of biological complexity. Proceedings of the National Academy of Sciences, 97, 4463-4468.
- ANSORGE, U., FRANCIS, G., HERZOG, M. H. & OĞMEN, H. 2008. Visual masking and the dynamics of human perception, cognition, and consciousness A century of progress, a contemporary synthesis, and future directions. Adv Cogn Psychol, 3, 1-8. [CrossRef]
- BANCROFT, T. & SERVOS, P. 2011. Distractor frequency influences performance in vibrotactile working memory. Experimental Brain Research, 208, 529-532. [CrossRef]
- BAZZARI, A. H. & PARRI, H. R. 2019. Neuromodulators and Long-Term Synaptic Plasticity in Learning and Memory: A Steered-Glutamatergic Perspective. Brain Sci, 9. [CrossRef]
- CAMPBELL, J. O. 2016. Universal Darwinism As a Process of Bayesian Inference. Front Syst Neurosci, 10, 49. [CrossRef]
- CEVIK, M. 2014. Habituation, sensitization, and Pavlovian conditioning. Front Integr Neurosci, 8, 13. [CrossRef]
- CHALMERS, D. J. & CHALMERS, D. J. 2010. 3Facing Up to the Problem of Consciousness. The Character of Consciousness. Oxford University Press.
- CORDES, C. 2006. Darwinism in economics: from analogy to continuity. Journal of Evolutionary Economics, 16, 529-541. [CrossRef]
- COWAN, N. 2001. The magical number 4 in short-term memory: A reconsideration of mental storage capacity. Behavioral and Brain Sciences, 24, 87-114. [CrossRef]
- COWAN, N. 2008. Chapter 20 What are the differences between long-term, short-term, and working memory? In: SOSSIN, W. S., LACAILLE, J.-C., CASTELLUCCI, V. F. & BELLEVILLE, S. (eds.) Progress in Brain Research. Elsevier.
- CRANO, W. D. 1977. Primacy versus recency in retention of information and opinion change. The Journal of Social Psychology, 101, 87-96. [CrossRef]
- DAWKINS, R. 1983. Universal darwinism. Evolution from molecules to men, 403-425.
- DE SPINOZA, B., CURLEY, E. & HAMPSHIRE, S. 1996. Ethics, Penguin Publishing Group.
- DICKINS, T. E. 2021. The Modern Synthesis. The Modern Synthesis: Evolution and the Organization of Information. Cham: Springer International Publishing.
- EDELMAN, G. 2004. Neural darwinism. New Persp. Q., 21, 62. [CrossRef]
- EKSTIG, B. 2015. Complexity, Natural Selection and the Evolution of Life and Humans. Found Sci, 20, 175-187. [CrossRef]
- FAUL, L. & LABAR, K. S. 2023. Mood-congruent memory revisited. Psychol Rev, 130, 1421-1456. [CrossRef]
- FODOR, J. A. & SOCIETY, B. P. 1987. Psychosemantics: The Problem of Meaning in the Philosophy of Mind, MIT Press.
- FRENCH, A. P. 2017. Special relativity, CRC Press.
- FRISTON, K. 2010. The free-energy principle: a unified brain theory? Nature Reviews Neuroscience, 11, 127-138. [CrossRef]
- GAZZALEY, A. & NOBRE, A. C. 2012. Top-down modulation: bridging selective attention and working memory. Trends Cogn Sci, 16, 129-35. [CrossRef]
- GINNS, P. 2006. Integrating information: A meta-analysis of the spatial contiguity and temporal contiguity effects. Learning and Instruction - LEARN INSTR, 16, 511-525. [CrossRef]
- HINTZMAN, D. L. 2016. Is memory organized by temporal contiguity? Memory & Cognition, 44, 365-375. [CrossRef]
- HORST, S. 1999. Symbols and Computation A Critique of the Computational Theory of Mind. Minds and Machines, 9, 347-381. [CrossRef]
- HUXLEY, J. 1942. Evolution. The modern synthesis.
- KENNEDY, M. B. 2013. Synaptic Signaling in Learning and Memory. Cold Spring Harb Perspect Biol, 8, a016824. [CrossRef]
- KIRK, G. S., RAVEN, J. E. & SCHOFIELD, M. 1983. The Presocratic Philosophers: A Critical History with a Selection of Texts, Cambridge University Press.
- LALAND, K. N., ULLER, T., FELDMAN, M. W., STERELNY, K., MÜLLER, G. B., MOCZEK, A., JABLONKA, E. & ODLING-SMEE, J. 2015. The extended evolutionary synthesis: its structure, assumptions and predictions. Proc Biol Sci, 282, 20151019. [CrossRef]
- LUPPI, A. I., SINGLETON, S. P., HANSEN, J. Y., JAMISON, K. W., BZDOK, D., KUCEYESKI, A., BETZEL, R. F. & MISIC, B. 2024. Contributions of network structure, chemoarchitecture and diagnostic categories to transitions between cognitive topographies. Nature Biomedical Engineering, 8, 1142-1161. [CrossRef]
- LYNCH, M., ACKERMAN, M. S., GOUT, J. F., LONG, H., SUNG, W., THOMAS, W. K. & FOSTER, P. L. 2016. Genetic drift, selection and the evolution of the mutation rate. Nat Rev Genet, 17, 704-714. [CrossRef]
- MASSIMINI, M., FERRARELLI, F., HUBER, R., ESSER, S. K., SINGH, H. & TONONI, G. 2005. Breakdown of Cortical Effective Connectivity During Sleep. Science, 309, 2228-2232. [CrossRef]
- MESOUDI, A., WHITEN, A. & LALAND, K. N. 2004. Perspective: Is human cultural evolution Darwinian? Evidence reviewed from the perspective of The Origin of Species. Evolution, 58, 1-11. [CrossRef]
- MONROE, J. G., SRIKANT, T., CARBONELL-BEJERANO, P., BECKER, C., LENSINK, M., EXPOSITO-ALONSO, M., KLEIN, M., HILDEBRANDT, J., NEUMANN, M., KLIEBENSTEIN, D., WENG, M.-L., IMBERT, E., ÅGREN, J., RUTTER, M. T., FENSTER, C. B. & WEIGEL, D. 2022. Mutation bias reflects natural selection in Arabidopsis thaliana. Nature, 602, 101-105. [CrossRef]
- MÜLLER, G. B. 2017. Why an extended evolutionary synthesis is necessary. Interface focus, 7, 20170015. [CrossRef]
- NELSON, R. R. 2007. Universal Darwinism and evolutionary social science. Biology & Philosophy, 22, 73-94. [CrossRef]
- NOBLE, D. 2012. A theory of biological relativity: no privileged level of causation. Interface Focus, 2, 55-64. [CrossRef]
- NOBLE, D. 2017. Evolution viewed from physics, physiology and medicine. Interface Focus, 7, 20160159. [CrossRef]
- PATRICK, B. & DOLAPO, A. 2025. The Hard Problem of Consciousness.
- PICCININI, G. 2015. Physical Computation: A Mechanistic Account, Oxford University Press.
- SAUNDERS, P. T. & HO, M. W. 1981. On the increase in complexity in evolution II. The relativity of complexity and the principle of minimum increase. Journal of Theoretical Biology, 90, 515-530. [CrossRef]
- SCHACTER, D. L., DOBBINS, I. G. & SCHNYER, D. M. 2004. Specificity of priming: a cognitive neuroscience perspective. Nature Reviews Neuroscience, 5, 853-862. [CrossRef]
- SCHUTZ, A. 1970. William James’s Concept of the Stream of Thought Phenomenologically Interpreted. In: SCHUTZ, A. & SCHUTZ, I. (eds.) Collected Papers III: Studies in Phenomenological Philosophy. Dordrecht: Springer Netherlands.
- SHAGRIR, O. 2005. The Rise and Fall of Computational Functionalism. In: BEN-MENAHEM, Y. (ed.) Hilary Putnam. Cambridge: Cambridge University Press.
- SHANNON, C. E. 1941. Mathematical Theory of the Differential Analyzer. Journal of Mathematics and Physics, 20, 337-354. [CrossRef]
- SHIFFRIN, R. 1993. Short-term memory: A brief commentary. Memory & cognition, 21, 193-7. [CrossRef]
- SIBURG, K. F. 2004. The Principle of Least Action in Geometry and Dynamics, Springer Berlin Heidelberg.
- SIGMAN, M. & DEHAENE, S. 2008. Brain mechanisms of serial and parallel processing during dual-task performance. J Neurosci, 28, 7585-98. [CrossRef]
- SIRAND-PUGNET, P., LARTIGUE, C., MARENDA, M., JACOB, D., BARRÉ, A., BARBE, V., SCHENOWITZ, C., MANGENOT, S., COULOUX, A., SEGURENS, B., DE DARUVAR, A., BLANCHARD, A. & CITTI, C. 2007. Being pathogenic, plastic, and sexual while living with a nearly minimal bacterial genome. PLoS Genet, 3, e75. [CrossRef]
- SMALLWOOD, J. & SCHOOLER, J. W. 2015. The Science of Mind Wandering: Empirically Navigating the Stream of Consciousness. Annual Review of Psychology, 66, 487-518. [CrossRef]
- SMOLIN, L. 2004. Cosmological natural selection as the explanation for the complexity of the universe. Physica A: Statistical Mechanics and its Applications, 340, 705-713. [CrossRef]
- SPREVAK, M. & SMITH, R. 2023. An Introduction to Predictive Processing Models of Perception and Decision--Making. Topics in Cognitive Science. [CrossRef]
- TAJUDDIN, BISWAS, M. H. A. & ISLAM, A. 2008. Review of the Theory of Relativity. Journal of Applied Sciences Research, 4, 32—39.
- TANG, M. F., FORD, L., ARABZADEH, E., ENNS, J. T., VISSER, T. A. W. & MATTINGLEY, J. B. 2020. Neural dynamics of the attentional blink revealed by encoding orientation selectivity during rapid visual presentation. Nature Communications, 11, 434. [CrossRef]
- TIPPER, S. P. 2001. Does negative priming reflect inhibitory mechanisms? A review and integration of conflicting views. The Quarterly Journal of Experimental Psychology Section A, 54, 321-343.
- TONONI, G. & KOCH, C. 2008. The Neural Correlates of Consciousness. Annals of the New York Academy of Sciences, 1124, 239-261.
- TRÜBUTSCHEK, D., MARTI, S., OJEDA, A., KING, J.-R., MI, Y., TSODYKS, M. & DEHAENE, S. 2017. A theory of working memory without consciousness or sustained activity. eLife, 6, e23871. [CrossRef]
- TULVING, E. & PEARLSTONE, Z. 1966. Availability versus accessibility of information in memory for words. Journal of Verbal Learning and Verbal Behavior, 5, 381-391. [CrossRef]
- TURING, A. 2004. On Computable Numbers, with an Application to the Entscheidungsproblem (1936). [CrossRef]
- WALD, R. M. 2024. General Relativity, University of Chicago Press.
- ZYLBERBERG, A., OUELLETTE, B., SIGMAN, M. & ROELFSEMA, P. R. 2012. Decision Making during the Psychological Refractory Period. Current Biology, 22, 1795-1799. [CrossRef]
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).