Submitted:
05 May 2025
Posted:
07 May 2025
You are already at the latest version
Abstract
Keywords:
A Preliminary Study on the Association Between ADHD Symptomatology and Pregnancy Distress: The Mediating Role of Self-Compassion and Self-Criticism
The Effect of ADHD Symptomatology on Pregnancy and Birth Outcomes
Pregnancy-Related Anxiety and Antenatal Depression
Self-Compassion as a Mediator in the Mental Health of People with ADHD Symptoms
The Current Study
Method
Participants
Materials
Procedure
Data Analysis Strategy
Results
Preliminary Data Analysis
Correlational Analysis
Mediation Analyses
Discussion
Limitations
Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- American Psychiatric Association issuing body. Diagnostic and statistical manual of mental disorders : DSM-5-TR, 5th edition, text revision; American Psychiatric Association Publishing: Washington, DC, 2022. [Google Scholar]
- Michelini, G.; Kitsune, V.; Vainieri, I.; Hosang, G.M.; Brandeis, D.; Asherson, P.; et al. Shared and disorder-specific event-related brain oscillatory markers of attentional dysfunction in ADHD and bipolar disorder. Brain Topography. 2018, 31, 672–89. [Google Scholar] [CrossRef]
- Hartman, C.A.; Rommelse, N.; van der Klugt, C.L.; Wanders, R.B.K.; Timmerman, M.E. Stress exposure and the course of ADHD from childhood to young adulthood: Comorbid severe emotion dysregulation or mood and anxiety problems. Journal of Clinical Medicine. 2019, 8, 1824. [Google Scholar] [CrossRef] [PubMed]
- Sayal, K.; Prasad, V.; Daley, D.; Ford, T.; Coghill, D. ADHD in children and young people: prevalence, care pathways, and service provision. The Lancet Psychiatry. 2018, 5, 175–86. [Google Scholar] [CrossRef] [PubMed]
- Zhu, Y.; Liu, W.; Li, Y.; Wang, X.; Winterstein, A.G. Prevalence of ADHD in publicly insured adults. Journal of Attention Disorders. 2018, 22, 182–90. [Google Scholar] [CrossRef]
- Biederman, J.; Petty, C.R.; Evans, M.; Small, J.; Faraone, S.V. How persistent is ADHD? A controlled 10-year follow-up study of boys with ADHD. Psychiatry Research. 2010, 177, 299–304. [Google Scholar] [CrossRef] [PubMed]
- Simon, V.; Czobor, P.; Bálint, S.; Mészáros, Á.; Bitter, I. Prevalence and correlates of adult attention-deficit hyperactivity disorder: meta-analysis. British Journal of Psychiatry. 2009, 194, 204–11. [Google Scholar] [CrossRef]
- Ginsberg, Y.; Quintero, J.; Anand, E.; Casillas, M.; Upadhyaya, H.P. Underdiagnosis of attention-deficit/hyperactivity disorder in adult patients: a review of the literature. Primary care companion for CNS disorders 2014, 16. [Google Scholar] [CrossRef]
- Klefsjö, U.; Kantzer, A.K.; Gillberg, C.; Billstedt, E. The road to diagnosis and treatment in girls and boys with ADHD - gender differences in the diagnostic process. Nordic Journal of Psychiatry. 2021, 75, 301–5. [Google Scholar] [CrossRef]
- Quinn, P.O.; Madhoo, M. A review of attention-deficit/hyperactivity disorder in women and girls: uncovering this hidden diagnosis. Primary care companion for CNS disorders 2014, 16. [Google Scholar] [CrossRef]
- Attoe, D. E.; Climie, E. A. Miss. Diagnosis: A systematic review of ADHD in adult women. Journal of Attention Disorders 2023, 27, 645–657. [Google Scholar] [CrossRef]
- Beaton, D.M.; Sirois, F.; Milne, E. Self-compassion and perceived criticism in adults with Attention Deficit Hyperactivity Disorder (ADHD). Mindfulness. 2020, 11, 2506–18. [Google Scholar] [CrossRef]
- Faraone, S.V.; Bellgrove, M.A.; Brikell, I.; Cortese, S.; Hartman, C.A.; Hollis, C.; et al. Attention-deficit/hyperactivity disorder (Primer). Nature Reviews Disease Primers. 2024, 10, 11. [Google Scholar] [CrossRef] [PubMed]
- Combs, M.A.; Canu, W.H.; Broman-Fulks, J.J.; Rocheleau, C.A.; Nieman, D.C. Perceived stress and ADHD symptoms in adults. Journal of Attention Disorders. 2015, 19, 425–34. [Google Scholar] [CrossRef]
- Stern, A.; Agnew-Blais, J.; Danese, A.; Fisher, H.L.; Jaffee, S.R.; Matthews, T.; et al. Associations between abuse/neglect and ADHD from childhood to young adulthood: A prospective nationally-representative twin study. Child Abuse & Neglect. 2018, 81, 274–85. [Google Scholar]
- Sari Gokten, E.; Saday Duman, N.; Soylu, N.; Uzun, M.E. Effects of attention-deficit/hyperactivity disorder on child abuse and neglect. Child Abuse & Neglect. 2016, 62, 1–9. [Google Scholar]
- Asherson, P.; Buitelaar, J.; Faraone, S.V.; Rohde, L.A. Adult attention-deficit hyperactivity disorder: key conceptual issues. The Lancet Psychiatry. 2016, 3, 568–78. [Google Scholar] [CrossRef] [PubMed]
- Friedrichs, B.; Igl, W.; Larsson, H.; Larsson, J.O. Coexisting psychiatric problems and stressful life events in adults with symptoms of ADHD—A large Swedish population-based study of twins. Journal of Attention Disorders. 2012, 16, 13–22. [Google Scholar] [CrossRef]
- Sahmurova, A.; Arikan, S.; Gursesli, M.C.; Duradoni, M. ADHD symptoms as a stressor leading to depressive symptoms among university students: The mediating role of perceived stress between ADHD and depression. International Journal of Environmental Research and Public Health. 2022, 19, 11091. [Google Scholar] [CrossRef]
- Kessler, R.C.; Adler, L.; Barkley, R.; Biederman, J.; Conners, C.K.; Demler, O.; et al. The Prevalence and Correlates of Adult ADHD in the United States: Results From the National Comorbidity Survey Replication. The American Journal of Psychiatry. 2006, 163, 716–23. [Google Scholar] [CrossRef]
- Torgersen, T.; Gjervan, B.; Rasmussen, K. ADHD in adults: A study of clinical characteristics, impairment and comorbidity. Nordic Journal of Psychiatry. 2006, 60, 38–43. [Google Scholar] [CrossRef]
- Fuller-Thomson, E.; Carrique, L.; MacNeil, A. Generalized anxiety disorder among adults with attention deficit hyperactivity disorder. Journal of Affective Disorders. 2022, 299, 707–14. [Google Scholar] [CrossRef] [PubMed]
- Walsh, C.J.; Rosenberg, S.L.; Hale, E.W. Obstetric complications in mothers with ADHD. Frontiers in Reproductive Health. 2022, 4, 1040824–1040824. [Google Scholar] [CrossRef] [PubMed]
- Jones, H.A.; Eddy, L.D.; Rabinovitch, A.E.; Snipes, D.J.; Wilson, S.A.; Parks, A.M.; et al. Attention-deficit/hyperactivity disorder symptom clusters differentially predict prenatal health behaviors in pregnant women. Journal of Clinical Psychology. 2018, 74, 665–79. [Google Scholar] [CrossRef] [PubMed]
- Eddy, L.D.; Jones, H.A.; Snipes, D.; Karjane, N.; Svikis, D. Associations between ADHD symptoms and occupational, interpersonal, and daily life impairments among pregnant women. Journal of Attention Disorders. 2019, 23, 976–84. [Google Scholar] [CrossRef]
- Kittel-Schneider, S.; Quednow, B.B.; Leutritz, A.L.; McNeill, R.V.; Reif, A. Parental ADHD in pregnancy and the postpartum period – a systematic review. Neuroscience and Biobehavioral Reviews. 2021, 124, 63–77. [Google Scholar] [CrossRef]
- Watson, B.; Fuller-Tyszkiewicz, M.; Broadbent, J.; Skouteris, H. The meaning of body image experiences during the perinatal period: A systematic review of the qualitative literature. Body Image. 2015, 14, 102–13. [Google Scholar] [CrossRef]
- Dryer, R.; Brunton, R. Pregnancy-related anxiety : Theory, research, and practice. Abingdon, Oxon; Routledge; 2022.
- Yin, X.; Sun, N.; Jiang, N.; Xu, X.; Gan, Y.; Zhang, J.; et al. Prevalence and associated factors of antenatal depression: Systematic reviews and meta-analyses. Clinical Psychology Review. 2021, 83, 101932–101932. [Google Scholar] [CrossRef]
- Dennis, C.L.; Falah-Hassani, K.; Shiri, R. Prevalence of antenatal and postnatal anxiety: Systematic review and meta-analysis. British Journal of Psychiatry. 2017, 210, 315–23. [Google Scholar] [CrossRef]
- Bayrampour, H.; Ali, E.; McNeil, D.A.; Benzies, K.; MacQueen, G.; Tough, S. Pregnancy-related anxiety: A concept analysis. International Journal of Nursing Studies. 2016, 55, 115–30. [Google Scholar] [CrossRef]
- Dryer, R.; Brunton, R.; Krägeloh, C.; Medvedev, O. Screening for pregnancy-related anxiety: Evaluation of the Pregnancy-Related Anxiety Scale–Screener using Rasch methodology. Assessment. 2023, 30, 1407–17. [Google Scholar] [CrossRef]
- Poikkeus, P.; Saisto, T.; Unkila-Kallio, L.; Punamaki, R. L. , Repokari, L., Vilska, S..; et al. Fear of childbirth and pregnancy-related anxiety in women conceiving with assisted reproduction. Obstetrics and Gynecology. 2006, 108, 70–76. [Google Scholar] [CrossRef] [PubMed]
- Robertson, E.; Grace, S.; Wallington, T.; Stewart, D.E. Antenatal risk factors for postpartum depression: a synthesis of recent literature. General Hospital Psychiatry. 2004, 26, 289–95. [Google Scholar] [CrossRef] [PubMed]
- Zelkowitz, P.; Papageorgiou, A. Easing maternal anxiety: An update. Women’s Health. 2012, 8, 205–13. [Google Scholar] [CrossRef]
- Ninowski, J.E.; Mash, E.J.; Benzies, K.M. Symptoms of attention-deficit/hyperactivity disorder in first-time expectant women: Relations with parenting cognitions and behaviors. Infant Mental Health Journal. 2007, 28, 54–75. [Google Scholar] [CrossRef] [PubMed]
- Murray, C.; Johnston, C. Parenting in mothers with and without attention-deficit/hyperactivity disorder. Journal of Abnormal Psychology. 2006, 115, 52–61. [Google Scholar] [CrossRef]
- Neff, K. Self-Compassion: An alternative conceptualization of a healthy attitude toward oneself. Self and Identity. 2003, 2, 85–101. [Google Scholar] [CrossRef]
- Brenner, R.E.; Heath, P.J.; Vogel, D.L.; Credé, M. Two is more valid than one: Examining the factor structure of the Self-Compassion Scale (SCS). Journal of Counseling Psychology. 2017, 64, 696–707. [Google Scholar] [CrossRef]
- Cleare, S.; Gumley, A.; Cleare, C.J.; O’Connor, R.C. An investigation of the factor structure of the Self-Compassion Scale. Mindfulness. 2018, 9, 618–628. [Google Scholar] [CrossRef]
- Löw, C.A.; Schauenburg, H.; Dinger, U. Self-criticism and psychotherapy outcome: A systematic review and meta-analysis. Clinical Psychology Review. 2020, 75, 101808–101808. [Google Scholar] [CrossRef]
- Langberg, J.M.; Epstein, J.N.; Graham, A.J. Organisational-skills interventions in the treatment of ADHD. Expert Review of Neurotherapeutics. 2008, 8, 1549–1561. [Google Scholar] [CrossRef]
- Beaton, D.M.; Sirois, F.; Milne, E. The role of self-compassion in the mental health of adults with ADHD. Journal of Clinical Psychology. 2022, 78, 2497–512. [Google Scholar] [CrossRef] [PubMed]
- Farmer, G.M.; Ohan, J.L.; Finlay-Jones, A.L.; Bayliss, D.M. Well-being and distress in university students with ADHD traits: The mediating roles of self-compassion and emotion regulation difficulties. Mindfulnness. 2022, 14, 448–459. [Google Scholar] [CrossRef]
- Gao, J.; Feng, Y.; Xu, S.; Wilson, A.; Li, H.; Wang, X.; et al. Appearance anxiety and social anxiety: A mediated model of self-compassion. Frontiers In Public Health. 2023, 11, 1105428–1105428. [Google Scholar] [CrossRef] [PubMed]
- Fong, M.; Loi, N.M. The mediating role of self-compassion in student psychological health. Australian Psychologist. 2016, 51, 431–41. [Google Scholar] [CrossRef]
- Neff, K.D.; McGehee, P. Self-compassion and psychological resilience among adolescents and young adults. Self and identity. 2010, 9, 225–40. [Google Scholar] [CrossRef]
- Neff, K. Self-compassion: Theory, method, research, and intervention. Annual Review of Psychology. 2023, 74, 193–218. [Google Scholar] [CrossRef]
- Hinshaw, S.P.; Nguyen, P.T.; O’Grady, S.M.; Rosenthal, E.A. Annual Research Review: Attention-deficit/hyperactivity disorder in girls and women: underrepresentation, longitudinal processes, and key directions. Journal of child psychology and psychiatry. 2022, 63, 484–96. [Google Scholar] [CrossRef]
- Muris, P.; Petrocchi, N. Protection or vulnerability? A meta-analysis of the relations between the positive and negative components of self-compassion and psychopathology. Clinical Psychology and Psychotherapy. 2017, 24(2), 373–383. [Google Scholar] [CrossRef]
- Brunton, R.J.; Dryer, R.; Krägeloh, C.; Saliba, A.; Kohlhoff, J.; Medvedev, O. The pregnancy-related anxiety scale: A validity examination using Rasch analysis. Journal of Affective Disorders. 2018, 236, 127–35. [Google Scholar] [CrossRef]
- Cox, J.; Holden, J.; Sagovsky, R. Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. British Journal of Psychiatry. 1987, 150, 782–6. [Google Scholar] [CrossRef]
- Heller, H.M.; Draisma, S.; Honig, A. Construct Validity and Responsiveness of Instruments Measuring Depression and Anxiety in Pregnancy: A Comparison of EPDS, HADS-A and CES-D. International Journal of Environmental Research and Public Health. 2022, 19, 7563. [Google Scholar] [CrossRef] [PubMed]
- Raes, F.; Pommier, E.; Neff, K.D.; Van Gucht, D. Construction and factorial validation of a short form of the Self-Compassion Scale. Clinical Psychology and Psychotherapy. 2011, 18, 250–5. [Google Scholar] [CrossRef] [PubMed]
- Hayes, J.A.; Lockard, A.J.; Janis, R.A.; Locke, B.D. Construct validity of the Self-Compassion Scale-Short Form among psychotherapy clients. Counselling Psychology Quarterly. 2016, 29, 405–22. [Google Scholar] [CrossRef]
- Kessler, R.C.; Adler, L.; Ames, M.; Demler, O.; Faraone, S.; Hiripi, E.; et al. The World Health Organization adult ADHD self-report scale (ASRS): a short screening scale for use in the general population. Psychological Medicine. 2005, 35, 245–56. [Google Scholar] [CrossRef]
- American Psychiatric Association, issuing body. Diagnostic and statistical manual of mental disorders : DSMIV-TR (4th edition, text revision.). American Psychiatric Association Publishing, 2000.
- Adler, L.A.; Faraone, S.V.; Sarocco, P.; Atkins, N.; Khachatryan, A. Establishing US norms for the Adult ADHD Self-Report Scale (ASRS-v1.1) and characterising symptom burden among adults with self-reported ADHD. International Journal of Clinical Practice (Esher). 2019, 73, e13260. [Google Scholar] [CrossRef] [PubMed]
- Schmider, E.; Ziegler, M.; Danay, E.; Beyer, L.; Bühner, M. Is it really robust? Reinvestigating the robustness of ANOVA against violations of the normal distribution assumption. Methodology. 2010, 6, 147–51. [Google Scholar] [CrossRef]
- Tabachnick, B.G.; Fidell, L.S.; Ullman, J.B. Using multivariate statistics, Seventh edition; Pearson, 2019. [Google Scholar]
- Field, A.P. Discovering statistics using IBM SPSS statistics, 6th ed.; Sage, 2024. [Google Scholar]
- Hayes, A.F. Introduction to mediation, moderation, and conditional process analysis : a regression-based approach; Guilford Press, 2013. [Google Scholar]
- Hunter, S.; Dickson, C. Women’s experiences of transition to motherhood and self-compassion. Journal of Family and Child Health. 2024, 1, 28–39. [Google Scholar] [CrossRef]
- Werner, A.M.; Tibubos, A.N.; Rohrmann, S.; Reiss, N. The clinical trait self-criticism and its relation to psychopathology: A systematic review – Update. Journal of Affective Disorders. 2019, 246, 530–47. [Google Scholar] [CrossRef]
- Beato, A.F.; Albuquerque, S.; Kömürcü Akik, B.; Costa, L.P.D.; Salvador, Á. Do maternal self-criticism and symptoms of postpartum depression and anxiety mediate the effect of history of depression and anxiety symptoms on mother-infant bonding? Parallel-serial mediation models. Frontiers in Psychology. 2022, 13, 858356–858356. [Google Scholar] [CrossRef]
- Filisetti, A.C.; Ferreira, I.M.F.; Neufeld, C.M. The relationship between self-efficacy and self- compassion: An integrative systematic review of the literature. Revista Brasileira de Terapias Cognitivas. 2023, 19, 187–202. [Google Scholar] [CrossRef]

| Demographic characteristic | N | M (SD) or % |
|---|---|---|
| Age a | 142 | 30.91 (4.83) |
| Gestational Weeks | 143 | 23.01 (4.83) |
| Parity | ||
| Nulliparous | 69 | 48.3% |
| Multiparous | 74 | 51.8%% |
| Employment | ||
| Full time | 74 | 51.7% |
| Part-time | 23 | 16.1% |
| Homemaker | 11 | 7.7% |
| Self employed | 11 | 7.7% |
| Unemployed | 16 | 11.2% |
| Other | 8 | 5.6% |
| Education | ||
| Highschool certificate | 19 | 13.3% |
| Trade certificate/diploma | 22 | 15.4% |
| University (undergraduate) | 57 | 39.9% |
| University (postgraduate) | 45 | 31.5% |
| Marital Status | ||
| Married/De Facto | 112 | 78.3% |
| Divorced/Separated | 1 | 0.7% |
| Single | 30 | 21.0% |
| Country of Residence b | ||
| Australia | 35 | 25.7% |
| New Zealand | 3 | 2.2% |
| United Kingdom | 35 | 25.7% |
| United States of America | 2 | 1.5% |
| Canada | 11 | 8.1% |
| Other | 50 | 36.8% |
| ADHD Diagnostic Status | ||
| Yes | 31 | 21.7% |
| No | 112 | 78.3% |
| ADHD medication c | ||
| Yes | 9 | 7.2% |
| No | 116 | 92.8% |
| ADHD medication before pregnancy | ||
| Yes | 22 | 15.4% |
| No | 103 | 72.0% |
| Not applicable | 18 | 12.6% |
| Previous mental health diagnosis d | ||
| Yes | 74 | 52.1% |
| No | 68 | 47.9% |
| Variables | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
|---|---|---|---|---|---|---|---|---|---|
| 1. Age | - | ||||||||
| 2. Gestation | -.07 | - | |||||||
| 3. Parity | .30** | -.14 | - | ||||||
| 4. MH diagnosis | .07 | -.12 | -.12 | - | |||||
| 5. ADHD diagnosis | .02 | -.11 | -.10 | .37** | - | ||||
| 6. ASRS | .04 | -.03 | .04 | .40** | .40** | - | |||
| 7. Self-Comp. | .17* | -.08 | -.05 | -.12 | -.03 | -.35** | - | ||
| 8. Self-Criticism | -.03 | .11 | -.01 | .28** | .08 | .47** | -.52** | - | |
| 9. PrAS | -.33** | .03 | .06 | .22* | -.04 | .38** | -.41** | .47** | - |
| 10. EPDS | -.22* | .12 | .08 | .14 | .04 | .32** | -.42** | .55** | .58** |
| Model | IV → M | M → DV [R2] | IV → DV (Direct effect) |
IV → DV (Indirect effect) |
95% CI |
|---|---|---|---|---|---|
| IV: ASRS DV: PrAS M: Self-compassion CO: Age, MH diagnosis |
-0.17** -0.46 |
-0.88* [.33] -0.29 |
0.29, SE = 0.12, p = .02 0.25 |
0.15, SE = 0.07 0.13, SE = 0.05 |
0.05, 0.29 0.03, 0.25 |
| IV: ASRS DV: PrAS M: Self-criticism CO: Age, MH diagnosis |
0.13**0.37 | 1.18** [.27] 0.36 |
0.29, SE = 0.11, p = .01 0.25 |
0.16, SE = 0.05 0.13, SE = 0.05 |
0.06, 0.27 0.04, 0.23 |
| IV: ASRS DV: EPDS M: Self-compassion CO: Age, MH diagnosis |
-0.12** -0.34 |
-0.33** [.26] -0.33 |
0.08, SE = 0.03, p = .01 0.23 |
0.04, SE = 0.01 0.11, SE = 0.04 |
0.02, 0.07 0.04, 0.20 |
| IV: ASRS DV: EPDS M: Self-Criticism CO: Age, MH diagnosis |
0.17** 0.45 |
0.48** [.34] 0.48 |
0.05, SE = 0.03, p = .18 0.13 |
0.08, SE = 0.02 0.22, SE = 0.06 |
0.04, 0.12 0.12, 0.34 |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).