Recognizing the urgent need to cultivate innovative solutions capable of navigating the complexity and uncertainty of our rapidly changing world, this pioneering article forges an unprecedented synthesis between the insights of evolutionary biology and the discipline of "social entrepreneurship" informed by "innovationology." By deeply integrating principles of adaptation, resilience, and symbiotic cooperation, the author presents a radically new framework for catalyzing breakthrough innovations that address societal challenges with unprecedented efficacy and durability. Drawing on diverse case studies and interdisciplinary research, this groundbreaking work unveils innovative design methodologies, organizational structures, and scaling strategies that emulate the generative, self-organizing patterns of living systems. The visionary ideas explored here represent a major leap forward in redefining the purpose and practice of innovation to align with the imperative of building a thriving, regenerative future for all.