Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

A Color-Detectable Vitamin C Controlled-Release System Fabricated Using Electrospinning

Version 1 : Received: 5 April 2024 / Approved: 7 April 2024 / Online: 7 April 2024 (10:58:15 CEST)

A peer-reviewed article of this Preprint also exists.

Shin, M.J. A Color-Detectable Vitamin C Controlled-Release System Fabricated Using Electrospinning. Polymers 2024, 16, 1347. Shin, M.J. A Color-Detectable Vitamin C Controlled-Release System Fabricated Using Electrospinning. Polymers 2024, 16, 1347.

Abstract

This study develops a vitamin C controlled-release system trackable via color changes as a function of vitamin C release. The system is composed of coaxial microfibers prepared via coaxial electrospinning, with a core of poly(ethylene oxide) (PEO) incorporating vitamin C, and a shell composed of polycaprolactone (PCL) containing polydiacetylene (PDA) as the color-changing material. The shell thickness was controlled by adjusting the amount of PCL ejected during electrospinning, allowing the regulation of the release rate of vitamin C. When vitamin C added to PEO penetrated the PCL layer, the color of PDA changed from blue to red, indicating a color change. The results of this study can be applied to devices that require immediate detection of vitamin C release levels.

Keywords

vitamin C; controlled-release system; electrospinning; polydiacetylene

Subject

Chemistry and Materials Science, Polymers and Plastics

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