Secondulfo, C.; Visco, V.; Virtuoso, N.; Fortunato, M.; Migliarino, S.; Rispoli, A.; La Mura, L.; Stellato, A.; Caliendo, G.; Settembre, E.; Galluccio, F.; Hamzeh, S.; Bilancio, G. Vitamin D: A Bridge between Kidney and Heart. Life2024, 14, 617.
Secondulfo, C.; Visco, V.; Virtuoso, N.; Fortunato, M.; Migliarino, S.; Rispoli, A.; La Mura, L.; Stellato, A.; Caliendo, G.; Settembre, E.; Galluccio, F.; Hamzeh, S.; Bilancio, G. Vitamin D: A Bridge between Kidney and Heart. Life 2024, 14, 617.
Secondulfo, C.; Visco, V.; Virtuoso, N.; Fortunato, M.; Migliarino, S.; Rispoli, A.; La Mura, L.; Stellato, A.; Caliendo, G.; Settembre, E.; Galluccio, F.; Hamzeh, S.; Bilancio, G. Vitamin D: A Bridge between Kidney and Heart. Life2024, 14, 617.
Secondulfo, C.; Visco, V.; Virtuoso, N.; Fortunato, M.; Migliarino, S.; Rispoli, A.; La Mura, L.; Stellato, A.; Caliendo, G.; Settembre, E.; Galluccio, F.; Hamzeh, S.; Bilancio, G. Vitamin D: A Bridge between Kidney and Heart. Life 2024, 14, 617.
Abstract
Chronic kidney disease (CKD) and cardiovascular disease (CVD) are highly prevalent conditions, each significantly contributing to the global burden of morbidity and mortality. CVD and CKD share a great number of common risk factor, such as hypertension, diabetes, obesity, and smoking among others. Their relationship extends beyond these factors, encompassing intricate interplay between the two systems. Within this complex network of pathophysiological processes, vitamin D has emerged as a potential linchpin, exerting influence over diverse physiological pathways implicated in both CKD and CVD. In recent years, scientific exploration has unveiled a close connection between these two prevalent conditions and vitamin D, a crucial hormone traditionally recognized for its role in bone health. This article aims to provide an extensive review of vitamin D's multifaceted and expanding actions concerning its involvement in CKD and CVD.
Medicine and Pharmacology, Endocrinology and Metabolism
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.