Vitamin D: A Bridge between Kidney and Heart

How to cite: Secondulfo, C.; Visco, V.; Virtuoso, N.; Fortunato, M.; Migliarino, S.; Rispoli, A.; La Mura, L.; Stellato, A.; Caliendo, G.; Settembre, E.; Galluccio, F.; Hamzeh, S.; Bilancio, G. Vitamin D: A Bridge between Kidney and Heart. Preprints 2024, 2024040295. https://doi.org/10.20944/preprints202404.0295.v1 Secondulfo, C.; Visco, V.; Virtuoso, N.; Fortunato, M.; Migliarino, S.; Rispoli, A.; La Mura, L.; Stellato, A.; Caliendo, G.; Settembre, E.; Galluccio, F.; Hamzeh, S.; Bilancio, G. Vitamin D: A Bridge between Kidney and Heart. Preprints 2024, 2024040295. https://doi.org/10.20944/preprints202404.0295.v1

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MDPI and ACS Style

Secondulfo, C.; Visco, V.; Virtuoso, N.; Fortunato, M.; Migliarino, S.; Rispoli, A.; La Mura, L.; Stellato, A.; Caliendo, G.; Settembre, E.; Galluccio, F.; Hamzeh, S.; Bilancio, G. Vitamin D: A Bridge between Kidney and Heart. Preprints 2024, 2024040295. https://doi.org/10.20944/preprints202404.0295.v1

APA Style

Secondulfo, C., Visco, V., Virtuoso, N., Fortunato, M., Migliarino, S., Rispoli, A., La Mura, L., Stellato, A., Caliendo, G., Settembre, E., Galluccio, F., Hamzeh, S., & Bilancio, G. (2024). Vitamin D: A Bridge between Kidney and Heart. Preprints. https://doi.org/10.20944/preprints202404.0295.v1

Chicago/Turabian Style

Secondulfo, C., Sarah Hamzeh and Giancarlo Bilancio. 2024 "Vitamin D: A Bridge between Kidney and Heart" Preprints. https://doi.org/10.20944/preprints202404.0295.v1

Abstract

Chronic kidney disease (CKD) and cardiovascular disease (CVD) are highly prevalent conditions, each significantly contributing to the global burden of morbidity and mortality. CVD and CKD share a great number of common risk factor, such as hypertension, diabetes, obesity, and smoking among others. Their relationship extends beyond these factors, encompassing intricate interplay between the two systems. Within this complex network of pathophysiological processes, vitamin D has emerged as a potential linchpin, exerting influence over diverse physiological pathways implicated in both CKD and CVD. In recent years, scientific exploration has unveiled a close connection between these two prevalent conditions and vitamin D, a crucial hormone traditionally recognized for its role in bone health. This article aims to provide an extensive review of vitamin D's multifaceted and expanding actions concerning its involvement in CKD and CVD.

Keywords

vitamin D; calcitriol; calcidiol; kidney disease; cardiovascular disease; hypertension; osteoporosis; mineral-bone disease; metabolic disease.

Subject

Medicine and Pharmacology, Endocrinology and Metabolism

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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