Version 1
: Received: 4 March 2024 / Approved: 6 March 2024 / Online: 6 March 2024 (13:19:55 CET)
How to cite:
Ramirez, G.A.; Pittiglio, M.; Tesfatsion, T.T.; Ray, K.P.; Cruces, W. An HPLC Method for Separation of Delta 9 THC from Delta 8 THC. Preprints2024, 2024030367. https://doi.org/10.20944/preprints202403.0367.v1
Ramirez, G.A.; Pittiglio, M.; Tesfatsion, T.T.; Ray, K.P.; Cruces, W. An HPLC Method for Separation of Delta 9 THC from Delta 8 THC. Preprints 2024, 2024030367. https://doi.org/10.20944/preprints202403.0367.v1
Ramirez, G.A.; Pittiglio, M.; Tesfatsion, T.T.; Ray, K.P.; Cruces, W. An HPLC Method for Separation of Delta 9 THC from Delta 8 THC. Preprints2024, 2024030367. https://doi.org/10.20944/preprints202403.0367.v1
APA Style
Ramirez, G.A., Pittiglio, M., Tesfatsion, T.T., Ray, K.P., & Cruces, W. (2024). An HPLC Method for Separation of Delta 9 THC from Delta 8 THC. Preprints. https://doi.org/10.20944/preprints202403.0367.v1
Chicago/Turabian Style
Ramirez, G.A., Kyle P Ray and Westley Cruces. 2024 "An HPLC Method for Separation of Delta 9 THC from Delta 8 THC" Preprints. https://doi.org/10.20944/preprints202403.0367.v1
Abstract
The surge in popularity of Delta-8 Tetrahydrocannabinol (D8-THC) products, coupled with a lack of stringent regulation and oversight, has given rise to concerns regarding consumer safety and compliance with existing laws. This article delves into the challenges posed by the unregulated sale of D8-THC products, emphasizing the potential for contamination with prohibited constituents, including Delta-9 Tetrahydrocannabinol (D9-THC). The 2018 Farm Bill dictates that D9-THC concentrations must not exceed 0.3%, necessitating precise testing methods for accurate validation. Existing testing procedures, particularly involving High-Performance Liquid Chromatography (HPLC), face difficulties in distinguishing between D8 and D9 peaks, necessitating adjustments in parameters to enhance accuracy. The development of more refined testing methodologies is crucial for companies to ensure compliance, prevent adverse health effects, and provide consumers with accurately characterized cannabinoid profiles in the products they purchase.
Chemistry and Materials Science, Analytical Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
