Salu, P.; Reindl, K.M. Advancements in Circulating Tumor Cell Research: Bridging Biology and Clinical Applications. Cancers2024, 16, 1213.
Salu, P.; Reindl, K.M. Advancements in Circulating Tumor Cell Research: Bridging Biology and Clinical Applications. Cancers 2024, 16, 1213.
Salu, P.; Reindl, K.M. Advancements in Circulating Tumor Cell Research: Bridging Biology and Clinical Applications. Cancers2024, 16, 1213.
Salu, P.; Reindl, K.M. Advancements in Circulating Tumor Cell Research: Bridging Biology and Clinical Applications. Cancers 2024, 16, 1213.
Abstract
Circulating tumor cells (CTCs) are cells released from the primary tumor and intravasate into the blood or lymphatic vessels, where they are transported to distant sites and act as seeds that initiate cancer metastases. Recent advances in CTC research have shown their relevance as prognostic markers for early and metastatic disease detection, predictive biomarkers for relapse, and response to medical intervention or therapy. The rapidly evolving landscape of CTC biology has opened new avenues for understanding cancer progression, metastasis, and treatment response. Additionally, translating these findings into clinical applications holds promise for improving cancer diagnostics, prognosis, and personalized therapeutic strategies. This review discusses the significance of CTCs in cancer research and their associated challenges. We explore recent developments in the detection and characterization of CTCs and their implications in cancer research and clinical practice.
Biology and Life Sciences, Biology and Biotechnology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
