Qi, L.; Yu, Y.; Tao, Z.; Liu, M.; Jiang, Y.; Yao, K.; Wang, Y. Optimizing Flexible Microelectrode Designs for Enhanced Efficacy in Electrical Stimulation Therapy. Preprints2024, 2024021507. https://doi.org/10.20944/preprints202402.1507.v1
APA Style
Qi, L., Yu, Y., Tao, Z., Liu, M., Jiang, Y., Yao, K., & Wang, Y. (2024). Optimizing Flexible Microelectrode Designs for Enhanced Efficacy in Electrical Stimulation Therapy. Preprints. https://doi.org/10.20944/preprints202402.1507.v1
Chicago/Turabian Style
Qi, L., Kai Yao and Yuheng Wang. 2024 "Optimizing Flexible Microelectrode Designs for Enhanced Efficacy in Electrical Stimulation Therapy" Preprints. https://doi.org/10.20944/preprints202402.1507.v1
Abstract
To investigate the impact of electrode structure on Electrical Stimulation Therapy (EST) for chronic wound healing, this study designed three variants of flexible microelectrodes (FMs) with Ag-Cu coverings (ACCs), each exhibiting distinct geometrical configurations: hexagonal, cross-shaped, and serpentine. These were integrated with PPY@PDA/PANI (3/6) hydrogel dressings. Comprehensive animal studies, coupled with detailed electrical and mechanical modeling and simulations, were conducted to assess their performance. Results indicated that the serpentine-shaped FM outperformed its counterparts in terms of flexibility and safety, exhibiting minimal thermal effects and a reduced risk of burns. Notably, FMs with metal coverings under 3% demonstrated promising potential for optoelectronic self-powering capabilities. Additionally, simulation data highlighted the significant influence of hydrogel non-uniformity on the distribution of electrical properties across the skin surface, providing critical insights for optimizing EST protocols when employing hydrogel dressings.
Engineering, Electrical and Electronic Engineering
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