A Successful Approach in Diagnosing Shiga - Toxin Producing Escherichia coli -Induced Colitis

How to cite: Melinte, V.; Văcăroiu, C.M.; Radu, A.M.; Cismaru, M.I.; Călinoiu, A.L.; Rusu, A.; Oprescu Macovei, A.M.; Ciocîrlan, M.; Tianu, E.C.; Mîrzan, L.; Mihăilă, D.E.; Trandafir, I.V.; Bugeac Mitacu, C.S.; Gheorghiță, V. A Successful Approach in Diagnosing Shiga - Toxin Producing Escherichia coli -Induced Colitis. Preprints 2024, 2024020438. https://doi.org/10.20944/preprints202402.0438.v1 Melinte, V.; Văcăroiu, C.M.; Radu, A.M.; Cismaru, M.I.; Călinoiu, A.L.; Rusu, A.; Oprescu Macovei, A.M.; Ciocîrlan, M.; Tianu, E.C.; Mîrzan, L.; Mihăilă, D.E.; Trandafir, I.V.; Bugeac Mitacu, C.S.; Gheorghiță, V. A Successful Approach in Diagnosing Shiga - Toxin Producing Escherichia coli -Induced Colitis. Preprints 2024, 2024020438. https://doi.org/10.20944/preprints202402.0438.v1

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MDPI and ACS Style

Melinte, V.; Văcăroiu, C.M.; Radu, A.M.; Cismaru, M.I.; Călinoiu, A.L.; Rusu, A.; Oprescu Macovei, A.M.; Ciocîrlan, M.; Tianu, E.C.; Mîrzan, L.; Mihăilă, D.E.; Trandafir, I.V.; Bugeac Mitacu, C.S.; Gheorghiță, V. A Successful Approach in Diagnosing Shiga - Toxin Producing Escherichia coli -Induced Colitis. Preprints 2024, 2024020438. https://doi.org/10.20944/preprints202402.0438.v1

APA Style

Melinte, V., Văcăroiu, C.M., Radu, A.M., Cismaru, M.I., Călinoiu, A.L., Rusu, A., Oprescu Macovei, A.M., Ciocîrlan, M., Tianu, E.C., Mîrzan, L., Mihăilă, D.E., Trandafir, I.V., Bugeac Mitacu, C.S., & Gheorghiță, V. (2024). A Successful Approach in Diagnosing Shiga - Toxin Producing Escherichia coli -Induced Colitis. Preprints. https://doi.org/10.20944/preprints202402.0438.v1

Chicago/Turabian Style

Melinte, V., Claudia Sorina Bugeac Mitacu and Valeriu Gheorghiță. 2024 "A Successful Approach in Diagnosing Shiga - Toxin Producing Escherichia coli -Induced Colitis" Preprints. https://doi.org/10.20944/preprints202402.0438.v1

Abstract

Shiga-like toxin producing Escherichia coli (STEC) is a well-known cause of foodborne acute diarrheic diseases especially in children and the elderly. The potentially fatal complications associated with toxin production range from bloody diarrhoea and ischemic colitis to kidney failure, haemolytic-uremic syndrome (HUS) and colon perforation. We describe a case and literature review of STEC – induced colitis, highlighting the clinical features, and the necessary tools for the best diagnosis approach and management. Facing challenging differential diagnosis ranging from ischemic colitis, inflammatory bowel disease, to infectious process due to a pathogenic or opportunistic agent, we practiced a step-by-step exploration. Beginning with bacteriological investigation, imagistic screening, and colonoscopy, we could rule out some of initial suppositions and reach the final diagnosis, also considering the pathological results. Although antibiotics are not indicated in this pathology, our patient did receive antibiotics, given the risk of translocation and colon perforation, without associating any complications, as HUS or peritonitis. Detailed and rigorous investigations along with a multi-speciality team are required for a prompt medical support. Coping the symptoms and refraining from further complications are the mainstem of the treatment.

Keywords

STEC, bloody diarrhoea, ischemic colitis, E coli

Subject

Medicine and Pharmacology, Gastroenterology and Hepatology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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