Research Progress on Benzimidazole Fungicides: A Review

Song Bai; Miaohe Zhang; Shouying Tang; Miao Li; Rong Wu; Suran Wan; Lijun Chen; Xian Wei; Feifei Li

doi:10.20944/preprints202401.1179.v1

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preprints.org > chemistry and materials science > organic chemistry > doi: 10.20944/preprints202401.1179.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Research Progress on Benzimidazole Fungicides: A Review

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Version 1 : Received: 15 January 2024 / Approved: 16 January 2024 / Online: 16 January 2024 (06:14:00 CET)

A peer-reviewed article of this Preprint also exists.

Bai, S.; Zhang, M.; Tang, S.; Li, M.; Wu, R.; Wan, S.; Chen, L.; Wei, X.; Li, F. Research Progress on Benzimidazole Fungicides: A Review. Molecules 2024, 29, 1218. Bai, S.; Zhang, M.; Tang, S.; Li, M.; Wu, R.; Wan, S.; Chen, L.; Wei, X.; Li, F. Research Progress on Benzimidazole Fungicides: A Review. Molecules 2024, 29, 1218.

Abstract

Benzimidazole fungicides are a class of highly effective, low-toxicity, systemic broad-spectrum fungicides developed in the 1960s and 1970s, based on the fungicidal activity of the benzimidazole ring structure. They exhibit biological activities including anticancer, antibacterial, and antiparasitic effects. Due to their particularly outstanding antibacterial properties, they are widely used in agriculture to prevent and control various plant diseases caused by fungi. The main products of benzimidazole fungicides include benomyl, carbendazim, thiabendazole, albendazole, thiophanate, thiophanate-methyl, fuberidazole, carbamic acid, and carbendazim salicylate. This article mainly reviews the physicochemical properties, toxicological properties, and disease control efficacy, and pesticide residue and detection technologies of the aforementioned nine benzimidazole fungicides and their main metabolite (2-aminobenzimidazole). On this basis, a brief outlook on the future research directions of benzimidazole fungicides is presented.

Keywords

benzimidazole fungicides; carbendazim; toxicity; disease prevention and control; determination methods

Subject

Chemistry and Materials Science, Organic Chemistry

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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