Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

The Potential of Probiotics in Disease Treatment: Mechanisms, Engineering, and Applications

Version 1 : Received: 11 January 2024 / Approved: 11 January 2024 / Online: 12 January 2024 (08:30:19 CET)

A peer-reviewed article of this Preprint also exists.

Liu, M.; Chen, J.; Dharmasiddhi, I.P.W.; Chen, S.; Liu, Y.; Liu, H. Review of the Potential of Probiotics in Disease Treatment: Mechanisms, Engineering, and Applications. Processes 2024, 12, 316. Liu, M.; Chen, J.; Dharmasiddhi, I.P.W.; Chen, S.; Liu, Y.; Liu, H. Review of the Potential of Probiotics in Disease Treatment: Mechanisms, Engineering, and Applications. Processes 2024, 12, 316.

Abstract

Probiotics, living microorganisms with demonstrated health benefits when administered in sufficient quantities, have a rich history as dietary supplements to benefit human health. Recently, understanding of their mechanisms in the gastrointestinal tract has prompted exploration of probiotics in treating human diseases. However, the effective and precise delivery of probiotics remains a significant challenge in therapeutic applications. Here, we review the mechanisms of action of probiotics in human health and the most advanced strategies for efficient probiotic delivery. We also discuss the potential applications of engineered probiotics in disease treatment. This review contributes insights into the evolving landscape of probiotic research for therapeutic applications.

Keywords

probiotics;action mechanisms;engineering strategies;living therapeutics

Subject

Biology and Life Sciences, Biology and Biotechnology

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