Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Image-Guided Adaptive Brachytherapy in Cervical Cancer: Integration of Ultrasound

Elena Manea
,
Elena Chitoran
ORCID logo ,
Vlad Rotaru
* ,
Sinziana-Octavia Ionescu
,
Dan Luca
* ,
Ciprian Cirimbei
* ,
Mihnea Alecu
,
Cristina Mirela Capsa
,
Bogdan Gafton
,
Iulian Prutianu
,
Dragos Serban
ORCID logo ,
Laurentiu Simion
Version 1 : Received: 22 December 2023 / Approved: 25 December 2023 / Online: 26 December 2023 (01:30:16 CET)

How to cite: Manea, E.; Chitoran, E.; Rotaru, V.; Ionescu, S.; Luca, D.; Cirimbei, C.; Alecu, M.; Capsa, C.M.; Gafton, B.; Prutianu, I.; Serban, D.; Simion, L. Image-Guided Adaptive Brachytherapy in Cervical Cancer: Integration of Ultrasound. Preprints 2023, 2023121766. https://doi.org/10.20944/preprints202312.1766.v1 Manea, E.; Chitoran, E.; Rotaru, V.; Ionescu, S.; Luca, D.; Cirimbei, C.; Alecu, M.; Capsa, C.M.; Gafton, B.; Prutianu, I.; Serban, D.; Simion, L. Image-Guided Adaptive Brachytherapy in Cervical Cancer: Integration of Ultrasound. Preprints 2023, 2023121766. https://doi.org/10.20944/preprints202312.1766.v1

Abstract

Cervical cancer remains a major public health problem. Despite the screening programs, cervical cancer is the second most commonly diagnosed cancer. Most of the cases occur in less developed countries, and it is the third leading cause of cancer death among females. In 2000–2007, the five-year relative survival rate for European women diagnosed with cervical cancer was 62%.[1] Standard treatment for locally advanced cervical cancer reveals external beam radiotherapy (EBRT) with concurrent chemotherapy followed by image-guided adaptive brachytherapy (IGABT) boost [2, 3]. In the last years, the Gynaecological (GYN) working group composed of Group Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) has developed new recommendations for the treatment of cervical cancer based on IGABT. The treatment plan includes 3-dimensional (3D) imaging based on magnetic resonance imaging (MRI) or computed tomography (CT), adaptive to the target volume and organ at risk [4–6]. The brachytherapy insertion is made under anaesthesia. At the time of the application insertion, the ultrasound is used to guide the dilatation of the uterine canal and assess the depth of the uterine cavity. In this paper, we review the data available in international literature about the use of ultrasound (US) in brachytherapy treatment of cervical cancer.

Keywords

cervical cancer; brachytherapy; ultrasound; image guided adaptive brachytherapy

Subject

Medicine and Pharmacology, Oncology and Oncogenics

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0
Get PDF Cite Share 0
Bookmark BibSonomy Mendeley Reddit Delicious
×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.