Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

A Review of the Ethnobotanical Use, Chemistry and Pharmacological Activities of Constituents Derived from the Plant Genus Geijera (Rutaceae)

Version 1 : Received: 21 December 2023 / Approved: 22 December 2023 / Online: 22 December 2023 (08:11:26 CET)

A peer-reviewed article of this Preprint also exists.

Dugan, D.; Bell, R.J.; Brkljača, R.; Rix, C.; Urban, S. A Review of the Ethnobotanical Use, Chemistry and Pharmacological Activities of Constituents Derived from the Plant Genus Geijera (Rutaceae). Metabolites 2024, 14, 81. Dugan, D.; Bell, R.J.; Brkljača, R.; Rix, C.; Urban, S. A Review of the Ethnobotanical Use, Chemistry and Pharmacological Activities of Constituents Derived from the Plant Genus Geijera (Rutaceae). Metabolites 2024, 14, 81.

Abstract

Geijera Schott is a plant genus of the Rutaceae Juss. (rue and citrus) family, comprising six species which are all native to Oceania. Of the plants belonging to this genus, the most significant species that has a customary use is Geijera parviflora, which was used by Indigenous Australians, primarily as a pain reliever. Herein, a comprehensive review of the literature published on the genus Geijera from 1930-2023 was conducted. This is the first review for this plant genus and it highlights the chemical constituents reported to date, together with the range of pharmacological properties described from the various species and different parts of the plant. These properties include anti-inflammatory, anti-microbial, anti-parasitic, insect repellent, analgesic, neuroactive, and anti-cancer activities. Finally, a reflection on some of the important areas for future focused studies of this plant genus is provided.

Keywords

Geijera; wilga; biological activity; pharmacology; customary use; analgesic; toothache; anti-cancer

Subject

Chemistry and Materials Science, Organic Chemistry

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