Viraneva, A.; Marudova, M.; Milenkova, S.; Grigorov, A.; Yovcheva, T. Investigation of Polyelectrolyte Multilayers Deposited on Biodegradable Corona-Charged Substrates Used as Drug Delivery Systems. Coatings2024, 14, 85.
Viraneva, A.; Marudova, M.; Milenkova, S.; Grigorov, A.; Yovcheva, T. Investigation of Polyelectrolyte Multilayers Deposited on Biodegradable Corona-Charged Substrates Used as Drug Delivery Systems. Coatings 2024, 14, 85.
Viraneva, A.; Marudova, M.; Milenkova, S.; Grigorov, A.; Yovcheva, T. Investigation of Polyelectrolyte Multilayers Deposited on Biodegradable Corona-Charged Substrates Used as Drug Delivery Systems. Coatings2024, 14, 85.
Viraneva, A.; Marudova, M.; Milenkova, S.; Grigorov, A.; Yovcheva, T. Investigation of Polyelectrolyte Multilayers Deposited on Biodegradable Corona-Charged Substrates Used as Drug Delivery Systems. Coatings 2024, 14, 85.
Abstract
Polyelectrolyte multilayers (PEMs) deposited on porous composite polylactic acid/poly(ε-caprolactone) substrates were studied. The substrates were previously charged in a corona discharge. Time dependences of the normalized surface potential for positively and negatively charged electrets were investigated. The morphology of the obtained porous substrates was examined by means of scanning electron microscopy (SEM). The chitosan and the casein polyelectrolytes were deposited on the substrates using the layer-by-layer (LbL) technique. A drug loading efficiency and the release kinetics were determined spectrophotometrically.
Keywords
porous composites; corona treatment; polyelectrolyte multilayers, drug delivery systems.
Subject
Physical Sciences, Condensed Matter Physics
Copyright:
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