Cancer Screening in Angolan Individuals Using Tumor Marker Tests at Mediag, Luanda-Angola

Edson Kutelela Cassinela; Lourenço Quixari; Silvana da Rocha Silveira; Cruz dos Santos Sebastião; António Armando; Carlos Pinto-Sousa; José Fernando; Manuel Sangombe Epalanga; Euclides Nenga Manuel Sacomboio

doi:10.20944/preprints202312.0168.v1

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preprints.org > medicine and pharmacology > oncology and oncogenics > doi: 10.20944/preprints202312.0168.v1

Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Cancer Screening in Angolan Individuals Using Tumor Marker Tests at Mediag, Luanda-Angola

Edson Kutelela Cassinela

^* ,

Lourenço Quixari

Silvana da Rocha Silveira

Cruz dos Santos Sebastião

António Armando

Carlos Pinto-Sousa

José Fernando

Manuel Sangombe Epalanga

Euclides Nenga Manuel Sacomboio

Version 1 : Received: 2 December 2023 / Approved: 4 December 2023 / Online: 4 December 2023 (11:40:55 CET)

How to cite: Cassinela, E.K.; Quixari, L.; Silveira, S.D.R.; Sebastião, C.D.S.; Armando, A.; Pinto-Sousa, C.; Fernando, J.; Epalanga, M.S.; Sacomboio, E.N.M. Cancer Screening in Angolan Individuals Using Tumor Marker Tests at Mediag, Luanda-Angola. Preprints 2023, 2023120168. https://doi.org/10.20944/preprints202312.0168.v1 Cassinela, E.K.; Quixari, L.; Silveira, S.D.R.; Sebastião, C.D.S.; Armando, A.; Pinto-Sousa, C.; Fernando, J.; Epalanga, M.S.; Sacomboio, E.N.M. Cancer Screening in Angolan Individuals Using Tumor Marker Tests at Mediag, Luanda-Angola. Preprints 2023, 2023120168. https://doi.org/10.20944/preprints202312.0168.v1

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MDPI and ACS Style

Cassinela, E.K.; Quixari, L.; Silveira, S.D.R.; Sebastião, C.D.S.; Armando, A.; Pinto-Sousa, C.; Fernando, J.; Epalanga, M.S.; Sacomboio, E.N.M. Cancer Screening in Angolan Individuals Using Tumor Marker Tests at Mediag, Luanda-Angola. Preprints 2023, 2023120168. https://doi.org/10.20944/preprints202312.0168.v1

APA Style

Cassinela, E.K., Quixari, L., Silveira, S.D.R., Sebastião, C.D.S., Armando, A., Pinto-Sousa, C., Fernando, J., Epalanga, M.S., & Sacomboio, E.N.M. (2023). Cancer Screening in Angolan Individuals Using Tumor Marker Tests at Mediag, Luanda-Angola. Preprints. https://doi.org/10.20944/preprints202312.0168.v1

Chicago/Turabian Style

Cassinela, E.K., Manuel Sangombe Epalanga and Euclides Nenga Manuel Sacomboio. 2023 "Cancer Screening in Angolan Individuals Using Tumor Marker Tests at Mediag, Luanda-Angola" Preprints. https://doi.org/10.20944/preprints202312.0168.v1

Abstract

Tumor biomarkers have great potential in screening and their role could extend further from general population risk assessment to treatment response estimation and recurrence monitoring. Different molecular and cellular elements in blood, which give information about the status of an individual, make it a perfect compartment to develop noninvasive diagnostics approaches for cancer. The present study aimed to screen the most frequent tumor markers in the Angolan population according to age and gender. A whole blood sample was collected for each patient. Serum levels were measured using the electrochemiluminescence method, using the automated Cobas e411 equipment (Roche®) according to the manufacturer's instructions. The results of our study elucidated the relevance of tumor biomarkers in screening for different types of cancer. These results also highlight the robustness of the mean in suspected cases, which is 15 to 17 times higher in some markers than in non-suspected cases. More research is needed to elucidate the relevance of these biomarkers in the Angolan population.

Keywords

tumor marker; screening; Angolan population

Subject

Medicine and Pharmacology, Oncology and Oncogenics

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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