Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Breast Cancer in the Tissue of the Contralateral Breast Reduction

Version 1 : Received: 30 November 2023 / Approved: 1 December 2023 / Online: 1 December 2023 (03:13:14 CET)

A peer-reviewed article of this Preprint also exists.

Kuijlaars, Z.M.A.; Hillberg, N.S.; Kooreman, L.; Severens Rijvers, C.A.H.; Qiu, S.S. Breast Cancer in the Tissue of the Contralateral Breast Reduction. Cancers 2024, 16, 497. Kuijlaars, Z.M.A.; Hillberg, N.S.; Kooreman, L.; Severens Rijvers, C.A.H.; Qiu, S.S. Breast Cancer in the Tissue of the Contralateral Breast Reduction. Cancers 2024, 16, 497.

Abstract

Breast cancer is the most prevalent malignancy among women globally. Early diagnosis and treatment improvements are leading to a growing population of survivors. This has increased the risk of developing contralateral breast cancer (CBC), a distinct occurrence in the opposite breast of a previously diagnosed patient. The treatment options for breast cancer are often mas-tectomy or lumpectomy. Patients with lumpectomy frequently undergo a contralateral reduc-tion procedure to achieve more symmetry after the primary breast cancer surgery. The reduc-tion specimen is usually routinely examined by pathology to check for malignancies. The exci-sion in pieces and the absence of specific markers or ink make an examination of tumor size and margin status more challenging, impacting treatment decisions. A new protocol introduced in July 2022 seeks to improve diagnostic precision and treatment planning by excision in toto, marking, and inking excised reduction tissue to examine and treat potential CBC more effectively.

Keywords

breast cancer; breast reduction; contralateral breast cancer

Subject

Medicine and Pharmacology, Oncology and Oncogenics

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