Oliveira, E.S.; Kohatsu, C.N.; Hufnagel, M.T.; Gennaro, V.F.; Demarque, D.P. New Compounds from Terrestrial Plants: A Perspective View. Compounds2024, 4, 415-440.
Oliveira, E.S.; Kohatsu, C.N.; Hufnagel, M.T.; Gennaro, V.F.; Demarque, D.P. New Compounds from Terrestrial Plants: A Perspective View. Compounds 2024, 4, 415-440.
Oliveira, E.S.; Kohatsu, C.N.; Hufnagel, M.T.; Gennaro, V.F.; Demarque, D.P. New Compounds from Terrestrial Plants: A Perspective View. Compounds2024, 4, 415-440.
Oliveira, E.S.; Kohatsu, C.N.; Hufnagel, M.T.; Gennaro, V.F.; Demarque, D.P. New Compounds from Terrestrial Plants: A Perspective View. Compounds 2024, 4, 415-440.
Abstract
In view of the diminishing contribution of natural products from plants to the discovery of new chemical structures, the aim of this study was to compile the articles from 2021 to 2022, assessing: (1) which classes of compounds these new structures belong to; (2) which plants and families these compounds belong to and (3) assessing the degree of novelty of the compound with an already known structure. The review was elaborate following the Preferred Reporting Items for System-atics Reviews and Meta-analyses (PRISMA) statement checklist for guide reporting of systematic reviews. A total of 464 articles were selected for the new compounds of natural origin survey. We included 117 complete articles in this review and reported approximately 109 new structures elucidated during the years 2021 and 2022. Many of the compounds showed small structural var-iations in relation to already known molecules. For some, however, this small modification was decisive for the biological activity reported, demonstrating the importance of descriptive phytochemical studies.
Keywords
natural products; new compounds; plants
Subject
Chemistry and Materials Science, Organic Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.