Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Prognostic Significance of Physiological and Biochemical Parameters in Colic-Afflicted Equine

Version 1 : Received: 13 November 2023 / Approved: 13 November 2023 / Online: 14 November 2023 (05:34:17 CET)

How to cite: Mickevičienė, I.; Mikalauskienė, D.; Dambrauskaitė, D.; Miknienė, Z. Prognostic Significance of Physiological and Biochemical Parameters in Colic-Afflicted Equine. Preprints 2023, 2023110809. https://doi.org/10.20944/preprints202311.0809.v1 Mickevičienė, I.; Mikalauskienė, D.; Dambrauskaitė, D.; Miknienė, Z. Prognostic Significance of Physiological and Biochemical Parameters in Colic-Afflicted Equine. Preprints 2023, 2023110809. https://doi.org/10.20944/preprints202311.0809.v1

Abstract

Colic, a primary cause of illness and death in horses, necessitates improved prognostic tools. We assessed the predictive value of physiological parameters in colic prognosis. A comprehensive clinical evaluation encompassed heart rate, mucous membranes, capillary refill time, rectal temperature, respiratory rate, gut motility, reflux, and limb pulse strength. Results reveal key predictors of fatal outcomes in colic-affected horses. Stomach reflux, absence of gut noises, and increased heart rate (mean increase of 12 bpm) strongly correlate with a poor prognosis. Prolonged capillary refill (mean increase of 3 seconds), elevated packed cell volume (mean increase of 4%), and blood lactate levels (mean increase of 5 mmol/L) underscore the significance of these markers. Notably, blood lactate (p < 0.001), gut noises (p < 0.05), and heart rate (p < 0.001) exhibit the highest predictive significance based on statistical analysis. Future research should explore the prognostic potential of additional parameters and assess the impact of recommended treatments on colic prognosis. This data-driven study emphasizes the critical role of early recognition and thorough assessment in colic cases, offering vital insights into improving equine healthcare and mitigating mortality rates.

Keywords

colic syndrome; equine; prognostic; survival; outcome; physiological; parameters; biochemical

Subject

Biology and Life Sciences, Animal Science, Veterinary Science and Zoology

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