Rong, G.; Sawan, M. Tamm Plasmon Polariton Biosensors Based on Porous Silicon: Design, Validation and Analysis. Biosensors2023, 13, 1026.
Rong, G.; Sawan, M. Tamm Plasmon Polariton Biosensors Based on Porous Silicon: Design, Validation and Analysis. Biosensors 2023, 13, 1026.
Rong, G.; Sawan, M. Tamm Plasmon Polariton Biosensors Based on Porous Silicon: Design, Validation and Analysis. Biosensors2023, 13, 1026.
Rong, G.; Sawan, M. Tamm Plasmon Polariton Biosensors Based on Porous Silicon: Design, Validation and Analysis. Biosensors 2023, 13, 1026.
Abstract
Tamm Plasmon Polariton (TPP) is a nanophotonic phenomenon that has attracted much attention due to its spatial strong field confinement, ease of mode excitation and polarization independence. TPP has applications in sensing, storage, lasing, perfect absorber, solar cell, nonlinear optics, and many others. In this work, we demonstrate a biosensing platform based on TPP resonant mode. Both theoretical analyses based on Transfer Matrix Method and experimental validation through nonspecific detection of liquids of different refractive indices and specific detection of SARS-CoV-2 nucleocapsid protein (N-protein) are presented. Results show that TPP biosensor has high sensitivity and good specificity. For N-protein detection, the sensitivity is 1.5 nm/(µg/ml) and the limit of detection can reach down to below 7 ng/ml with spectrometer of 0.01 nm resolution of wavelength shift. This work paves the way for design, optimization, fabrication, characterization, and performance analysis of TPP based biosensors
Keywords
Tamm Plasmon Polariton; Optical Biosensor; Porous Silicon; Nucleocapsid Protein; SARS-CoV-2
Subject
Engineering, Electrical and Electronic Engineering
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
