Review
Version 1
Preserved in Portico This version is not peer-reviewed
Biological Properties and Biomedical Applications of Pectin and Pectin-Based Composites: A Review
Version 1
: Received: 20 October 2023 / Approved: 23 October 2023 / Online: 25 October 2023 (08:11:48 CEST)
A peer-reviewed article of this Preprint also exists.
Sultana, N. Biological Properties and Biomedical Applications of Pectin and Pectin-Based Composites: A Review. Molecules 2023, 28, 7974. Sultana, N. Biological Properties and Biomedical Applications of Pectin and Pectin-Based Composites: A Review. Molecules 2023, 28, 7974.
Abstract
Due to its distinctive chemical and biological properties, pectin has recently drawn much attention in biomedical and tissue engineering applications. Polymers like pectin with cell-instructive properties are attractive natural biomaterials for tissue repair and regeneration. Besides, bioactive pectin and pectin-based composites exhibit improved characteristics to deliver active molecules. Pectin and pectin-based composites serve as interactive matrices or scaffolds by stimulating cell adhesion and cell proliferation and enhancing tissue remodeling by forming an extracellular matrix in vivo. Several bioactive properties, such as immunoregulatory, antibacterial, anti-inflammatory, anti-tumor, and antioxidant activities, contribute to the pectin's and pectin-based composite's enhanced applications in tissue engineering and drug delivery systems.This paper reviews the promising characteristics of pectin or pectic polysaccharides and highlights its potential applications in drug delivery and tissue engineering. Tissue engineering scaffolds containing pectin and pectin-based conjugates or composites demonstrate essential features such as non-toxicity, tunable mechanical properties, biodegradability, and suitable surface properties. The design and fabrication of pectic composites are versatile for tissue engineering and drug delivery applications.
Keywords
Pectin; Tissue Engineering; Composites; Biomedical Applications
Subject
Chemistry and Materials Science, Biomaterials
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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