Version 1
: Received: 22 October 2023 / Approved: 23 October 2023 / Online: 23 October 2023 (11:12:37 CEST)
How to cite:
Ibrahim, I.; Ayariga, J.; Xu, J.; Robertson, B.K.; Ajayi, O. Exploring the Synergy of Carbon Nanodots in Enhancing Cannabidiol Delivery and Therapeutic Efficacy: A Comprehensive Review. Preprints2023, 2023101434. https://doi.org/10.20944/preprints202310.1434.v1
Ibrahim, I.; Ayariga, J.; Xu, J.; Robertson, B.K.; Ajayi, O. Exploring the Synergy of Carbon Nanodots in Enhancing Cannabidiol Delivery and Therapeutic Efficacy: A Comprehensive Review. Preprints 2023, 2023101434. https://doi.org/10.20944/preprints202310.1434.v1
Ibrahim, I.; Ayariga, J.; Xu, J.; Robertson, B.K.; Ajayi, O. Exploring the Synergy of Carbon Nanodots in Enhancing Cannabidiol Delivery and Therapeutic Efficacy: A Comprehensive Review. Preprints2023, 2023101434. https://doi.org/10.20944/preprints202310.1434.v1
APA Style
Ibrahim, I., Ayariga, J., Xu, J., Robertson, B.K., & Ajayi, O. (2023). Exploring the Synergy of Carbon Nanodots in Enhancing Cannabidiol Delivery and Therapeutic Efficacy: A Comprehensive Review. Preprints. https://doi.org/10.20944/preprints202310.1434.v1
Chicago/Turabian Style
Ibrahim, I., Boakai K. Robertson and Olufemi Ajayi. 2023 "Exploring the Synergy of Carbon Nanodots in Enhancing Cannabidiol Delivery and Therapeutic Efficacy: A Comprehensive Review" Preprints. https://doi.org/10.20944/preprints202310.1434.v1
Abstract
The dynamic interaction between carbon nanodots (CNDs) and cannabidiol (CBD) has captured significant attention as an innovative avenue for redefining drug delivery and amplifying therapeutic effectiveness. This in-depth review delves into the intricate synergy between these two elements, unveiling their profound potential in medicine. Commencing with an examination of the unique characteristics of CNDs and the techniques governing their synthesis, we discuss their versatility as drug carriers, highlighting their invaluable role in advancing CBD delivery. Cannabidiol, a non-psychoactive compound sourced from cannabis, has emerged as a focal point for its diverse therapeutic attributes. Nevertheless, the limitations posed by its restricted bioavailability and susceptibility to degradation pose substantial hindrances to realizing its full potential. Here, we elucidate how the amalgamation of CBD with CNDs transcends these challenges. We delve into the mechanisms that underlie this synergy, such as the augmentation of solubility and the safeguarding of CBD against premature breakdown, providing an intricate analysis. We will also journey you through a comprehensive exploration of diverse CBD loading techniques onto CNDs, dissecting the realms of physical encapsulation, covalent bonding, and adsorption processes. In summation, the combination of CNDs and CBD presents an extraordinary opportunity to elevate therapeutic outcomes. This synergetic paradigm masterfully tackles pivotal challenges in drug delivery, thereby paving the path for pioneering medical solutions.
Keywords
carbon nanodots (CNDs); cannabidiol (CBD); drug delivery; encapsulation; bioavailability; adsorption
Subject
Biology and Life Sciences, Immunology and Microbiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
