Pătrîntașu, D.-E.; Sárközi, H.K.; Lupușor, E.; Vlangăr, I.E.; Rotariu, G.-M.; Rența, I.-A.; Nan, A.-N.; Budin, C.E. A Multidisciplinary Approach as A Goal for the Management of Complications in Systemic Scleroderma: A Literature Review and Case Scenario. Diagnostics2023, 13, 3332.
Pătrîntașu, D.-E.; Sárközi, H.K.; Lupușor, E.; Vlangăr, I.E.; Rotariu, G.-M.; Rența, I.-A.; Nan, A.-N.; Budin, C.E. A Multidisciplinary Approach as A Goal for the Management of Complications in Systemic Scleroderma: A Literature Review and Case Scenario. Diagnostics 2023, 13, 3332.
Pătrîntașu, D.-E.; Sárközi, H.K.; Lupușor, E.; Vlangăr, I.E.; Rotariu, G.-M.; Rența, I.-A.; Nan, A.-N.; Budin, C.E. A Multidisciplinary Approach as A Goal for the Management of Complications in Systemic Scleroderma: A Literature Review and Case Scenario. Diagnostics2023, 13, 3332.
Pătrîntașu, D.-E.; Sárközi, H.K.; Lupușor, E.; Vlangăr, I.E.; Rotariu, G.-M.; Rența, I.-A.; Nan, A.-N.; Budin, C.E. A Multidisciplinary Approach as A Goal for the Management of Complications in Systemic Scleroderma: A Literature Review and Case Scenario. Diagnostics 2023, 13, 3332.
Abstract
Systemic sclerosis (also known as scleroderma) is a chronic fibrosing autoimmune disease with both skin and multisystem organ involvement. Scleroderma has the highest mortality among all rheumatic diseases. The pathophysiology mechanism of systemic sclerosis is a progressive self-amplifying process, which implicates the widespread microvascular damage, followed by a dysregulation of innate and adaptive immunity and inflammation, and diffuse fibrosis of the skin and visceral organs. Fibrosis of internal organs is a hint for systemic sclerosis, moreover associated with interstitial lung disease (SSc-ILD) is a complex process. We report a case of a 56 years old female, diagnosed with Systemic Sclerosis 16 years ago. The systemic and clinical manifestations, respiratory functional tests, radiological aspects and specific therapy were discussed.
Medicine and Pharmacology, Pathology and Pathobiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
