PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Association of Polymeric Immunoglobulin Receptor Gene’s Single Nucleotide Polymorphisms with the Growth and Disease-Resistant in Chicken F2 Resource Population
Version 1
: Received: 17 August 2023 / Approved: 18 August 2023 / Online: 21 August 2023 (03:11:16 CEST)
How to cite:
He, J.; Xie, L.; Liang, Q.; Liu, T.; Luo, C.; Xu, X.; Yuan, Y.; Hao, Q.; Shu, D.; Ji, J. Association of Polymeric Immunoglobulin Receptor Gene’s Single Nucleotide Polymorphisms with the Growth and Disease-Resistant in Chicken F2 Resource Population. Preprints2023, 2023081353. https://doi.org/10.20944/preprints202308.1353.v1
He, J.; Xie, L.; Liang, Q.; Liu, T.; Luo, C.; Xu, X.; Yuan, Y.; Hao, Q.; Shu, D.; Ji, J. Association of Polymeric Immunoglobulin Receptor Gene’s Single Nucleotide Polymorphisms with the Growth and Disease-Resistant in Chicken F2 Resource Population. Preprints 2023, 2023081353. https://doi.org/10.20944/preprints202308.1353.v1
He, J.; Xie, L.; Liang, Q.; Liu, T.; Luo, C.; Xu, X.; Yuan, Y.; Hao, Q.; Shu, D.; Ji, J. Association of Polymeric Immunoglobulin Receptor Gene’s Single Nucleotide Polymorphisms with the Growth and Disease-Resistant in Chicken F2 Resource Population. Preprints2023, 2023081353. https://doi.org/10.20944/preprints202308.1353.v1
APA Style
He, J., Xie, L., Liang, Q., Liu, T., Luo, C., Xu, X., Yuan, Y., Hao, Q., Shu, D., & Ji, J. (2023). Association of Polymeric Immunoglobulin Receptor Gene’s Single Nucleotide Polymorphisms with the Growth and Disease-Resistant in Chicken F2 Resource Population. Preprints. https://doi.org/10.20944/preprints202308.1353.v1
Chicago/Turabian Style
He, J., Dingming Shu and Jian Ji. 2023 "Association of Polymeric Immunoglobulin Receptor Gene’s Single Nucleotide Polymorphisms with the Growth and Disease-Resistant in Chicken F2 Resource Population" Preprints. https://doi.org/10.20944/preprints202308.1353.v1
Abstract
Polymeric immunoglobulin receptor (pIgR) plays an important role in mediating mucosal defenses, but the association between its single nucleotide polymorphisms (SNPs) and traits (such as growth and disease-resistant) in birds is scarcely known. In this research, we aimed to detect the single nucleotide polymorphisms of the pIgR gene in the chicken F2 resource population and discern the possible associations between pIgR SNPs and chicken growth, disease-resistant, respectively. Six-SNPs (3, 9, 15, 16, 19, and 21) in chicken (Gallus gallus) were significantly associated with disease-resistant in the pIgR gene (P < 0.05). The major allele genotype with SNP 9 and SNP 19 occurred more frequently with high Newcastle Disease Virus (NDV) antibody rates; the major allele genotype with the SNP 3 was predominant in those with significantly lower NDV antibody rates (P < 0.05); heterozygous with the SNP 15 and SNP 21 occurred more frequently with high avian leukemia virus (ALV) antibody rates; the TT genotypes with the SNP 16 was predominant in those with low infectious bursal disease (IBD) antibody rates (P < 0.05). Besides, SNP 12 showed significant associations with body weights (BW) and shank lengths (SL) (P < 0.05). Genotyping revealed that the C allele occurred more frequently in breeds with high growth rates and the T allele was predominant in those with low growth rates at 8, 10, and 12w of age (P < 0.05). This polymorphic site may serve as a useful target for the marker assisted selection of growth and disease-resistant traits in chicken.
Biology and Life Sciences, Animal Science, Veterinary Science and Zoology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
