Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Cost-effectiveness of Glucosamine in Osteoarthritis Treatment: A Systematic Review

Nam Xuan Vo
* ORCID logo ,
Ngan Nguyen Hoang Le
,
Trinh Dang Phuong Chu
,
Huong Lai Pham
,
Khang Xuan An Dinh
,
Uyen Thi Thuc Che
,
Thanh Thi Thanh Ngo
,
Tien Thuy Bui
Version 1 : Received: 27 July 2023 / Approved: 28 July 2023 / Online: 28 July 2023 (11:25:01 CEST)

A peer-reviewed article of this Preprint also exists.

Vo, N.X.; Le, N.N.H.; Chu, T.D.P.; Pham, H.L.; Dinh, K.X.A.; Che, U.T.T.; Ngo, T.T.T.; Bui, T.T. Cost-Effectiveness of Glucosamine in Osteoarthritis Treatment: A Systematic Review. Healthcare 2023, 11, 2340. Vo, N.X.; Le, N.N.H.; Chu, T.D.P.; Pham, H.L.; Dinh, K.X.A.; Che, U.T.T.; Ngo, T.T.T.; Bui, T.T. Cost-Effectiveness of Glucosamine in Osteoarthritis Treatment: A Systematic Review. Healthcare 2023, 11, 2340.

Abstract

The osteoarthritis (OA), the main cause of disability, is a chronic condition that most frequently affects older adults. As the population ages, the cost of treatment is placing pressure on the healthcare budget. As a result, it is imperative to evaluate the medicines' cost-effectiveness and the influence they have on health resource allocation. Hence, our study aims to summarize the cost and outcome of utilizing glucosamine in OA treatment. Authentic databases like Medline, Cochrane, and Scopus were adopted for the identification process up until July 2023. Our primary inclusion criteria centered on the economic evaluation of Glucosamine in OA treatments with provided the incremental cost-effectiveness ratio (ICER) at least. The Quality of Health Economic Studies (QHES) instrument was applied to grade the quality of the studies. A total of 7 qualified studies were selected and discussed the cost-effectiveness of glucosamine with or without other formulations. All of them demonstrated that glucosamine was cost-effective. There was an in-creasement of QALY when incorporating Glucosamine into conventional care. Moreover, Crystalline Glucosamine Sulfate (pCGS) was more cost-effective than the Other Formulations of Glucosamine (OFG). In overall, utilizing pCGS was more beneficial than OFG in terms both of cost and quality of life.

Keywords

economic evaluation; cost-effectiveness; glucosamine; osteoarthritis; systematic review

Subject

Medicine and Pharmacology, Pharmacy

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF Download Supplementary

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0
Get PDF Supplementary Files Cite Share 0
Bookmark BibSonomy Mendeley Reddit Delicious
×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.