Colic, N.; Stevic, R.; Stjepanovic, M.; Savić, M.; Jankovic, J.; Belic, S.; Petrovic, J.; Bogosavljevic, N.; Aleksandric, D.; Lukic, K.; et al. Correlation between Radiological Characteristics, PET-CT and Histological Subtypes of Primary Lung Adenocarcinoma—A 102 Case Series Analysis. Medicina 2024, 60, 617, doi:10.3390/medicina60040617.
Colic, N.; Stevic, R.; Stjepanovic, M.; Savić, M.; Jankovic, J.; Belic, S.; Petrovic, J.; Bogosavljevic, N.; Aleksandric, D.; Lukic, K.; et al. Correlation between Radiological Characteristics, PET-CT and Histological Subtypes of Primary Lung Adenocarcinoma—A 102 Case Series Analysis. Medicina 2024, 60, 617, doi:10.3390/medicina60040617.
Colic, N.; Stevic, R.; Stjepanovic, M.; Savić, M.; Jankovic, J.; Belic, S.; Petrovic, J.; Bogosavljevic, N.; Aleksandric, D.; Lukic, K.; et al. Correlation between Radiological Characteristics, PET-CT and Histological Subtypes of Primary Lung Adenocarcinoma—A 102 Case Series Analysis. Medicina 2024, 60, 617, doi:10.3390/medicina60040617.
Colic, N.; Stevic, R.; Stjepanovic, M.; Savić, M.; Jankovic, J.; Belic, S.; Petrovic, J.; Bogosavljevic, N.; Aleksandric, D.; Lukic, K.; et al. Correlation between Radiological Characteristics, PET-CT and Histological Subtypes of Primary Lung Adenocarcinoma—A 102 Case Series Analysis. Medicina 2024, 60, 617, doi:10.3390/medicina60040617.
Abstract
Summarizing radiological characteristics between primary lung adenocarcinoma subtypes and correlate them with FDG uptake on PET-CT are important for further treatment. A PET-CT examination was performed on some of the patients and the values of SUV-max were also correlated with the histological and morphological characteristics of masses in the lungs. Results of this analysis showed that the mean size of AIS-MIA cancer was significantly lower than for all other cancer types, while mean size of the acinar cancer was smaller than in solid type of cancer. Metastases were significantly more frequent in solid adenocarcinoma than in acinar, lepidic and AIS-MIA cancer subtypes. The maximum standardized FDG uptake was significantly lower in AIS-MIA than in all other cancer types, and in acinar compared to solid cancer. Papillary adenocarcinoma had higher odds to develop contralateral lymph node involvement compared to other types. Solid adenocarcinoma was associated with higher odds of having metastases and with higher SUVmax. AIS-MIA was associated with lower odds of one unit increase in tumour size, ipsilateral lymph node involvement. Radiology has a significant role in the diagnosis and monitoring of the disease, and in determining its prognosis, and influence on the decision on the method of treatment.
Keywords
lung adenocarcinoma; CT; PET-CT; lung cancer
Subject
Medicine and Pharmacology, Oncology and Oncogenics
Copyright:
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