Feng, W.; Xiao, Q.; Wang, L.; Yang, Y. A New Fluorescent Probe for Hydrogen Sulfide Detection in Solution and Living Cells. Molecules2023, 28, 6195.
Feng, W.; Xiao, Q.; Wang, L.; Yang, Y. A New Fluorescent Probe for Hydrogen Sulfide Detection in Solution and Living Cells. Molecules 2023, 28, 6195.
Feng, W.; Xiao, Q.; Wang, L.; Yang, Y. A New Fluorescent Probe for Hydrogen Sulfide Detection in Solution and Living Cells. Molecules2023, 28, 6195.
Feng, W.; Xiao, Q.; Wang, L.; Yang, Y. A New Fluorescent Probe for Hydrogen Sulfide Detection in Solution and Living Cells. Molecules 2023, 28, 6195.
Abstract
Since Hydrogen Sulfide (H2S) was recognized as a gas transmitter, its detection and quantifica-tion have become a hot research topic among chemists and biologists. In this area. fluorescent probes have shown great advantages: fast and strong responds, low detection limit and easy ma-nipulation. Here we developed a new fluorescent probe that detected H2S selectively among various bioactive and inorganic salts. This probe was based on the core structure of fluorescein and reacted with H2S through azide-reduction. Great linearity was achieved correlating fluores-cence intensity and H2S concentrations in solution. The detection of H2S in cancer cells was also achieved.
Chemistry and Materials Science, Analytical Chemistry
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