Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Efficacy Study of a Dietary Supplement Containing Collagen‐L‐Arginine‐Hyaluronic Acid in Elderly Patients with Musculoskeletal Complaints

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Version 1 : Received: 16 June 2023 / Approved: 19 June 2023 / Online: 19 June 2023 (07:19:00 CEST)

How to cite: Fritz, P.; Mayer, L.; Bóday, P.; Maszlag, A.; Fritz, R. Efficacy Study of a Dietary Supplement Containing Collagen‐L‐Arginine‐Hyaluronic Acid in Elderly Patients with Musculoskeletal Complaints. Preprints 2023, 2023061307. https://doi.org/10.20944/preprints202306.1307.v1 Fritz, P.; Mayer, L.; Bóday, P.; Maszlag, A.; Fritz, R. Efficacy Study of a Dietary Supplement Containing Collagen‐L‐Arginine‐Hyaluronic Acid in Elderly Patients with Musculoskeletal Complaints. Preprints 2023, 2023061307. https://doi.org/10.20944/preprints202306.1307.v1

Abstract

The demand for dietary supplements containing collagen has been growing for years. The speciality and uniqueness of the dietary supplement (DS) examined in our study is the presence of L-arginine and hyaluronic acid alongside collagen and vitamin C. The individual mechanisms of action and physiological role of these compounds are understood, but they have not yet been tested in the combination and amounts of the dietary supplement used in this study. In this study, we investigated the effectiveness of the DS in elderly patients with musculoskeletal complaints. Somatometric, body composition, physiotherapy and laboratory tests were performed at the beginning and at the end of the study. The two-month study involved 30 people, randomly divided into two groups: a control group (CG) and an experimental group (EG). All subjects consumed 25 ml DS per day and EG members also participated in physiotherapy 3 times a week. Alongside the DS, blood lipid levels changed: LDL decreased, HDL increased, LDL/HDL ratio significantly decreased in both groups. For EG, the results improved more markedly. In 3 items of the body composition test, there was a significant improvement in both groups, which was attributed to the use of the dietary supplement. For the EG, there were significant changes in 5 additional test items, which we attribute to the addition of regular physical activity. Knee and hip joint range of motion (ROM) showed significant improvements in the study group, while in the CG the DS can cause significant improvements in joint range of motion in a passive condition as well.

Keywords

diatary supplement; body composition; laboratory results; collagen and hyaluron acid oral supplementation; articular movement improvement; C vitamin; L-arginin; health promotion

Subject

Public Health and Healthcare, Physical Therapy, Sports Therapy and Rehabilitation

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