Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Recent Advances on Electrospun Fibers for Biological Applications

Version 1 : Received: 12 June 2023 / Approved: 13 June 2023 / Online: 13 June 2023 (09:57:19 CEST)

A peer-reviewed article of this Preprint also exists.

Fromager, B.; Marhuenda, E.; Louis, B.; Bakalara, N.; Cambedouzou, J.; Cornu, D. Recent Advances in Electrospun Fibers for Biological Applications. Macromol 2023, 3, 569-613. Fromager, B.; Marhuenda, E.; Louis, B.; Bakalara, N.; Cambedouzou, J.; Cornu, D. Recent Advances in Electrospun Fibers for Biological Applications. Macromol 2023, 3, 569-613.

Abstract

Electrospinning is a simple versatile method to generate nanofibres. Remarkable progress has been made in the development of electrospinning process. The production of nanofibers is affected by many parameters, which influence the final material properties. Electrospun fibers have a wide range of applications such as energy storage and biomedical scaffolds. Polyacrylonitrile (PAN) has been widely used in the production of carbon nanofibers. PAN has received increasing interest in recent years, due to its excellent characteristics, such as spinnability, biocompatibility, and commercial viability, opening new applications in the biotechnological field. This paper provides an overview of the electrospinning process, its main parameters, and operation modes that affect nanofibers fabrication. A review of their biological applications is proposed. A focus is made on PAN fibers formation, functionalization, and application as scaffolds to allow cell growth. Overall, nanofibre scaffolds, made of stabilized PAN, appear as a powerful tool in medical applications needing controlled cell culture.

Keywords

electrospinning, single needle, multi-needle, polyacrylonitrile, nanofibers, parameters, scaffold, biological application, tissues engineering, cell culture.

Subject

Chemistry and Materials Science, Biomaterials

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