Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Influence of Dynamics of Changes in the Physical Properties of Osteoconductive Granulated Biopolymers on Scafold Stability in the Postoperative Period

Oleg V. Slesarev
* ,
Darya V. Malchikova
ORCID logo ,
Vladimir I. Platonov
,
Natalia A. Maksimenko
,
Alexey A. Melnikov
,
Mariya A. Anikina
,
Ravshanbek B. Abdullaev
Version 1 : Received: 19 May 2023 / Approved: 22 May 2023 / Online: 22 May 2023 (05:09:23 CEST)

How to cite: Slesarev, O.V.; Malchikova, D.V.; Platonov, V.I.; Maksimenko, N.A.; Melnikov, A.A.; Anikina, M.A.; Abdullaev, R.B. Influence of Dynamics of Changes in the Physical Properties of Osteoconductive Granulated Biopolymers on Scafold Stability in the Postoperative Period. Preprints 2023, 2023051464. https://doi.org/10.20944/preprints202305.1464.v1 Slesarev, O.V.; Malchikova, D.V.; Platonov, V.I.; Maksimenko, N.A.; Melnikov, A.A.; Anikina, M.A.; Abdullaev, R.B. Influence of Dynamics of Changes in the Physical Properties of Osteoconductive Granulated Biopolymers on Scafold Stability in the Postoperative Period. Preprints 2023, 2023051464. https://doi.org/10.20944/preprints202305.1464.v1

Abstract

Osteoconductive granulated biopolymers (OGB) are used to restore the lost volume of the jaw bone. OGB is employed as a loose fraction and exhibits physical traits common to bulk mixtures. By removing air bubbles and industrial dust from the OGB fraction through special processing, more accessible spaces are left over for the adsorption of bone growth factors. The recipient site's biological environment alters the OGB fraction's physical characteristics. This is the cause of the OGB fraction's volume changing uncontrollably during the first three weeks following surgery. Predictive indicators for describing the physical processes of osteoconduction include the compaction coefficient and adsorption capacity. Taking into account the prognostic indicators of the dynamics of changes in the physical properties of the OGB fraction in the postoperative period, 3D planning of the bioengineered structure should be done. The OGB fraction's adsorption and drainage properties are optimized by raising the purity of OGB production and preparing the biopolymer for clinical studies.

Keywords

osteoconduction; osteoconductive granulated biopolymers; compaction coefficient; adsorption capacity; bone growth factors

Subject

Medicine and Pharmacology, Dentistry and Oral Surgery

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0
Get PDF Cite Share 0
Bookmark BibSonomy Mendeley Reddit Delicious
×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.