Review
Version 1
Preserved in Portico This version is not peer-reviewed
A Polymer Instigated Path in the Engineering of Sensors and Biosensors for Effective Amelioration of Therapeutics
Version 1
: Received: 15 May 2023 / Approved: 16 May 2023 / Online: 16 May 2023 (09:34:09 CEST)
A peer-reviewed article of this Preprint also exists.
Quazi, M.Z.; Hwang, J.; Song, Y.; Park, N. Hydrogel-Based Biosensors for Effective Therapeutics. Gels 2023, 9, 545. Quazi, M.Z.; Hwang, J.; Song, Y.; Park, N. Hydrogel-Based Biosensors for Effective Therapeutics. Gels 2023, 9, 545.
Abstract
Nanotechnology and polymer engineering are steering towards a new development to invade deleterious mysteries. In the last few decades, polymer engineering has grabbed researchers’ attention and similarly, polymeric network-engineered structures have been vastly studied. Prior to therapeutic application, early and quick detection analyses are critical. Therefore, developing nanoscale sensors to manage the acute expression of feeble states and malignancies to draw therapeutic lines demands advanced nanoengineering. In spite of nano-therapeutics have emerged as an alternative approach to tackling strenuous diseases. Also, studies have shown highly biocompatible biomedical engineering has emerged with sheer progression. Moreover, hydrogels have emerged as a three-dimensional (3D) polymeric network that consists of hydrophilic natural or synthetic polymers. The resemblance of hydrogels with tissue structure makes it more unique to study inquisitively. Preceding studies have shown a vast spectrum of synthetic and natural polymer deployment in the field of biotechnology and molecular diagnostics. This review explores recent studies on synthetic and natural polymer engineered hydrogel-based biosensors and their applications in multipurpose diagnostics and therapeutics. We reviewed the latest studies on hydrogel-engineered biosensors, exclusively DNA-based and DNA hydrogels fabricated biosensors.
Keywords
DNA-based hydrogels; biosensors; stimuli-responsive; Progesterone detection; mRNA quantification; sensors
Subject
Chemistry and Materials Science, Biomaterials
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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