Version 1
: Received: 11 May 2023 / Approved: 12 May 2023 / Online: 12 May 2023 (08:49:10 CEST)
Version 2
: Received: 13 October 2023 / Approved: 13 October 2023 / Online: 16 October 2023 (08:54:50 CEST)
Wade, S.F.; Diouara, A.A.M.; Ngom, B.; Thiam, F.; Dia, N. SARS-CoV-2 and Other Respiratory Viruses in Human Olfactory Pathophysiology. Microorganisms2024, 12, 540.
Wade, S.F.; Diouara, A.A.M.; Ngom, B.; Thiam, F.; Dia, N. SARS-CoV-2 and Other Respiratory Viruses in Human Olfactory Pathophysiology. Microorganisms 2024, 12, 540.
Wade, S.F.; Diouara, A.A.M.; Ngom, B.; Thiam, F.; Dia, N. SARS-CoV-2 and Other Respiratory Viruses in Human Olfactory Pathophysiology. Microorganisms2024, 12, 540.
Wade, S.F.; Diouara, A.A.M.; Ngom, B.; Thiam, F.; Dia, N. SARS-CoV-2 and Other Respiratory Viruses in Human Olfactory Pathophysiology. Microorganisms 2024, 12, 540.
Abstract
Acute respiratory viruses (ARVs) are leading cause of diseases in human worldwide. High risk individuals including children and elderly could potentially develop severe illness that could result in hospitalization or death in the worst case. Most common ARVs are Human respiratory syncytial virus, Human Metapneumovirus, Human Parainfluenza Virus, rhinovirus, coronaviruses (including SARS and MERS CoV), adenoviruses, Human Bocavirus, enterovirus (-D68 and 71), and influenza viruses. The olfactory deficits due to ARVs infection is a common symptom among patients. This mini review provides an overview of the role of SARS-CoV-2 and other common ARVs in the development of human olfactory pathophysiology. We highlight the critical need for understanding the signaling underlying the olfactory dysfunction and the development of therapeutics for this wide-ranging category of AVRs to restore the altered or loss of smell in affected patients.
Keywords
Respiratory viruses; Anosmia; Olfaction Disorders; loss of smell; Covid-19
Subject
Biology and Life Sciences, Virology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
