Version 1
: Received: 11 May 2023 / Approved: 12 May 2023 / Online: 12 May 2023 (08:49:10 CEST)
How to cite:
Wade, S.F.; Diouara, A.A.M.; Ngom, B.; Thiam, F.; Dia, N. SARS-CoV-2 and Other Respiratory Viruses in Human Olfactory Pathophysiology. Preprints.org2023, 2023050906. https://doi.org/10.20944/preprints202305.0906.v1
Wade, S.F.; Diouara, A.A.M.; Ngom, B.; Thiam, F.; Dia, N. SARS-CoV-2 and Other Respiratory Viruses in Human Olfactory Pathophysiology. Preprints.org 2023, 2023050906. https://doi.org/10.20944/preprints202305.0906.v1
Cite as:
Wade, S.F.; Diouara, A.A.M.; Ngom, B.; Thiam, F.; Dia, N. SARS-CoV-2 and Other Respiratory Viruses in Human Olfactory Pathophysiology. Preprints.org2023, 2023050906. https://doi.org/10.20944/preprints202305.0906.v1
Wade, S.F.; Diouara, A.A.M.; Ngom, B.; Thiam, F.; Dia, N. SARS-CoV-2 and Other Respiratory Viruses in Human Olfactory Pathophysiology. Preprints.org 2023, 2023050906. https://doi.org/10.20944/preprints202305.0906.v1
Abstract
The novel coronavirus disease 2019 (COVID-19) known as severe acute respiratory syndrome - coronavirus 2 (SARS-CoV-2) has emerged in China in 2019, and caused an outbreak of unusual viral pneumonia. The olfactory dysfunction following the infection of different variants of SARS-CoV-2 is now accepted as a hallmark symptom in patients. Recent studies have pointed out the relationship between COVID-19 and altered or loss of smell in infected patients. This mini review provides an overview of the role of SARS-CoV-2 and the other acute respiratory viruses in the development the human olfactory pathophysiology. We highlight the importance of deciphering the molecular mechanisms underlying the olfactory dysfunction caused by SARS-CoV-2 to help design new drugs to restore the altered or loss of smell in affected patients.
Keywords
Respiratory viruses; Anosmia; Olfaction Disorders; loss of smell; COVID-19
Subject
Biology and Life Sciences, Virology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
