Version 1
: Received: 10 March 2023 / Approved: 14 March 2023 / Online: 14 March 2023 (12:49:24 CET)
How to cite:
DeBlauw, J.A.; Churchill, A.; Yunda, B.; Kotarsky, C.J.; Caldwell, A.; Ives, S.J. The Effects of Short-Term Caloric Restriction on Cardiometabolic Health in Overweight/Obese Men and Women. Preprints2023, 2023030257. https://doi.org/10.20944/preprints202303.0257.v1
DeBlauw, J.A.; Churchill, A.; Yunda, B.; Kotarsky, C.J.; Caldwell, A.; Ives, S.J. The Effects of Short-Term Caloric Restriction on Cardiometabolic Health in Overweight/Obese Men and Women. Preprints 2023, 2023030257. https://doi.org/10.20944/preprints202303.0257.v1
DeBlauw, J.A.; Churchill, A.; Yunda, B.; Kotarsky, C.J.; Caldwell, A.; Ives, S.J. The Effects of Short-Term Caloric Restriction on Cardiometabolic Health in Overweight/Obese Men and Women. Preprints2023, 2023030257. https://doi.org/10.20944/preprints202303.0257.v1
APA Style
DeBlauw, J.A., Churchill, A., Yunda, B., Kotarsky, C.J., Caldwell, A., & Ives, S.J. (2023). The Effects of Short-Term Caloric Restriction on Cardiometabolic Health in Overweight/Obese Men and Women. Preprints. https://doi.org/10.20944/preprints202303.0257.v1
Chicago/Turabian Style
DeBlauw, J.A., Abigail Caldwell and Stephen J. Ives. 2023 "The Effects of Short-Term Caloric Restriction on Cardiometabolic Health in Overweight/Obese Men and Women" Preprints. https://doi.org/10.20944/preprints202303.0257.v1
Abstract
Overweight and Obesity (Ow/Ob) is a risk factor for developing cardiometabolic disease, and metabolic dysfunction. Dietary interventions, such as caloric restriction (CR), have been explored but little is known about the acute effects of CR and often such diets are not standardized. PURPOSE: To assess the impact of a standardized 3-day CR diet (~590kcal/d) on cardiometabolic health and fat metabolism in Ow/Ob individuals. METHODS: Fifteen Ow/Ob men and women were assessed pre-post 3-day CR using standardized diet; specifically, body weight/composition (% body fat, visceral fat score (Vfs), waist-hip circumferences, blood pressure and vascular stiffness, resting energy expenditure (REE), substrate utilization (respiratory quotient, RQ), and blood glucose/lipid profile. RESULTS: CR induced changes in body weight (93.1±15.2 to 90.67±14.4 kg, p<0.001, d=1.9), body mass index (32.9±4.0 to 32.0±3.7 kg/m2, p<0.001, d=1.4), body fat (37.2±7.5 to 35.8±7.5%, p=0.002, d=1.1) and Vfs (13.1±4.5 to 12.2±3.9 a.u., p=0.002, d=1.1), but not body water (46.3±3.6 to 46.0±3.6%, p=0.29, d=0.3). CR had no effect on peripheral (86±5 to 89±5 mmHg, p=0.23, d=0.3) or central mean arterial pressure (86±5 to 87±6 mmHg, p=0.44, d=0.2), but lowered augmentation index (29.8±17.5 to 21.5±14.5%, p=0.05, d=0.6). Blood glucose (86±7 to 84±11 mg/dl, p=0.33, d=0.3) and blood lipids (total cholesterol (196±49 to 203±54 mg/dl, p=0.16, d=0.4) and TC/HDL (4.9±2.4 to 6.1±4.7, p=0.13, d=0.4)) were unchanged. RQ decreased with CR (0.84±0.01 to 0.76±0.00, p<0.001, d=1.9), though REE was unchanged (1718±274 to 1722±317 kcal/d, p=0.83, d=0.1). CONCLUSION: The 3-day CR significantly improved body weight and composition and fat metabolism, with minimal cardiovascular effects.
Medicine and Pharmacology, Dietetics and Nutrition
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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