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Lobe X of the Cerebellum: A Natural Neuro-resistant Region
Version 1
: Received: 28 November 2022 / Approved: 29 November 2022 / Online: 29 November 2022 (08:41:51 CET)
A peer-reviewed article of this Preprint also exists.
Hernández-Pérez, C.; Weruaga, E.; Díaz, D. Lobe X of the Cerebellum: A Natural Neuro-Resistant Region. Anatomia 2023, 2, 43-62. Hernández-Pérez, C.; Weruaga, E.; Díaz, D. Lobe X of the Cerebellum: A Natural Neuro-Resistant Region. Anatomia 2023, 2, 43-62.
Abstract
The cerebellum is an encephalic region classically known for its central role in the control of movement, although recent research has revealed its involvement in other cognitive and affective tasks. Several different pathologies are known to affect this structure, causing a wide range of behavioral and gait impairments. Intriguingly, although the neurodegenerative factors affect all Purkinje cells of the cerebellum uniformly, certain neurodegeneration patterns can be distinguished, in which some Purkinje cells persist longer than other cell types. Precisely, there is a cerebellar region, lobe X, which is more resistant to different types of neurodegeneration regardless of the injury. This work will review the main models of cerebellar degeneration, with special emphasis on this region, and aims to reveal a common origin for its resistance to neuronal death.
Keywords
Cerebellum; lobe X; neurodegeneration; neuro-resistance
Subject
Biology and Life Sciences, Anatomy and Physiology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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