Version 1
: Received: 11 November 2022 / Approved: 15 November 2022 / Online: 15 November 2022 (03:23:47 CET)
How to cite:
Bulur, A.; Sivritepe, R. The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus. Preprints2022, 2022110270. https://doi.org/10.20944/preprints202211.0270.v1
Bulur, A.; Sivritepe, R. The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus. Preprints 2022, 2022110270. https://doi.org/10.20944/preprints202211.0270.v1
Bulur, A.; Sivritepe, R. The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus. Preprints2022, 2022110270. https://doi.org/10.20944/preprints202211.0270.v1
APA Style
Bulur, A., & Sivritepe, R. (2022). The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus. Preprints. https://doi.org/10.20944/preprints202211.0270.v1
Chicago/Turabian Style
Bulur, A. and Ridvan Sivritepe. 2022 "The Association between Non-Alcoholic Fatty Liver Disease and Dynapenia in Men Diagnosed with Type 2 Diabetes Mellitus" Preprints. https://doi.org/10.20944/preprints202211.0270.v1
Abstract
Background: Dynapenia and non-alcoholic fatty liver disease (NAFLD) are common, especially in the middle and advanced-age diabetic male population. We aimed to examine the clinical features, NAFLD severity, and parameters associated with the presence of dynapenia in type 2 diabetes mellitus (T2DM) cases. Material and Methods: One hundred thirty-five male patients diagnosed with T2DM between 45 and 65 years of age were included. Patients were staged by ultrasonography according to NAFLD status. Results: There were significant differences in muscle strength, upper arm circumference, calf circumference, and up-and-go test scores between the NAFLD groups (p<0.001 for all). The frequency of dynapenia was lower, and arm and calf circumferences were higher in patients without NAFLD. The muscle strength, upper arm circumference, calf circumference, and up-and-go test scores were significantly lower in the dynapenic group compared to the non-dynapenic group (p<0.005 for all). The prevalence of dynapenia increased along with the increase in NAFLD stages (p<0.001). Conclusions: We detected a significant association between NAFLD and dynapenia in middle-aged men with T2DM. As muscle strength decreases, the amount of fat in the liver increases, and as the fat in the liver increases, muscle strength decreases.
Keywords
type 2 diabetes mellitus; non-alcoholic fatty liver disease; dynapenia
Subject
Biology and Life Sciences, Biology and Biotechnology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
