Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Viral Detection of Suspected Sporadic Mumps in Gwangju, South Korea in 2021

Version 1 : Received: 30 August 2022 / Approved: 31 August 2022 / Online: 31 August 2022 (07:11:53 CEST)

How to cite: Mun, J.; Kim, S.; Park, J.W.; Park, J.; Park, S.J.; Lee, S.H.; Seo, J.J.; Chung, Y. Viral Detection of Suspected Sporadic Mumps in Gwangju, South Korea in 2021. Preprints 2022, 2022080535. https://doi.org/10.20944/preprints202208.0535.v1 Mun, J.; Kim, S.; Park, J.W.; Park, J.; Park, S.J.; Lee, S.H.; Seo, J.J.; Chung, Y. Viral Detection of Suspected Sporadic Mumps in Gwangju, South Korea in 2021. Preprints 2022, 2022080535. https://doi.org/10.20944/preprints202208.0535.v1

Abstract

Mumps is the second-most reported infectious disease in South Korea; however, due to the low pathogen confirmation rate in laboratory diagnoses, we proposed a method for reevaluating the high incidence rate via the laboratory verification of other viral diseases. In 2021, 63 cases of pharyngeal or cheek mucosal swabs of suspected mumps cases in Gwangju, South Korea, were assessed for causative pathogens using massive simultaneous pathogen testing (TaqManTM Array Cards). More than one respiratory virus was detected in 60 cases (95.2%), 44 (73.3%) of which were co-detected. Human rhinovirus was detected in 47 cases, followed by human herpesvirus (HHV)6 in 30; HHV4 (17), human bocavirus (17), HHV5 (10), and human parainfluenza virus 3 (6) were also detected. Our findings suggest the need for further investigations on the pathogenesis of diseases mimicking mumps, which are considered to aid with appropriate public health responses, treatment, and the prevention of infectious disease outbreaks.

Keywords

mumps; parotitis; parotid gland extenstion; salivary gland; respiratory virus; human herpesvirus 4 (HHV4); human herpesvirus 6 (HHV6)

Subject

Biology and Life Sciences, Virology

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