Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Multifunctional Eco-Friendly Synthesis of ZnO Nanoparticles in Biomedical Applications

Version 1 : Received: 13 December 2021 / Approved: 15 December 2021 / Online: 15 December 2021 (15:17:48 CET)

A peer-reviewed article of this Preprint also exists.

Al-Mohaimeed, A.M.; Al-Onazi, W.A.; El-Tohamy, M.F. Multifunctional Eco-Friendly Synthesis of ZnO Nanoparticles in Biomedical Applications. Molecules 2022, 27, 579. Al-Mohaimeed, A.M.; Al-Onazi, W.A.; El-Tohamy, M.F. Multifunctional Eco-Friendly Synthesis of ZnO Nanoparticles in Biomedical Applications. Molecules 2022, 27, 579.

Journal reference: Molecules 2022, 27, 579
DOI: 10.3390/molecules27020579

Abstract

This study describes an eco-friendly synthesis of ZnO nanoparticles using aqueous oat extract. The advanced electrochemical and optical features of green synthesized ZnONPs displayed excellent antibacterial activity, and exhibited an important role in pharmaceutical determinations. The formation of nanoscale ZnO was confirmed using various spectroscopic and microscopic investigations. The formed nanoparticles were found to be around 100 nm. The as-prepared ZnONPs were monitored for their antibacterial potential against different bacterial strains. The inhibition zones for ZnONPs were found as E. coli (16 mm), P. aeruginosa (17 mm), S. aureus (12 mm) and B. subtilis (11 mm) using 30 µg mL-1 sample concentration. Also, ZnONPs exhibited significant antioxidant effects 58 to 67 % with an average IC50 value of 0.88 ± 0.03 scavenging activity and 53 to 71 % (IC50 value 0.73 ± 0.05) against the DPPH and ABTS scavenging free radicals, respectively. The photocatalytic potential of ZnONPs for Rhodamine B dye degradation dye under UV irradiation was performed. The photodegradation process was carried out as a function of time-dependent and the complete degradation (nearly 98 %) with color removal after 120 min. Conclusively, the synthesized ZnONPs using oat biomass might provide a great promise in the future for biomedical applications.

Keywords

Oat extract; Zinc oxide nanoparticles; Green synthesis; Antibacterial; Antioxidant; Pharmaceutical analysis.

Subject

CHEMISTRY, Analytical Chemistry

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