PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
The Residual Efficacy of SumiShield™ 50WG and K-Othrine® WG250 IRS Formulations Applied to Different Building Materials Against Anopheles and Aedes Mosquitoes
Version 1
: Received: 9 November 2021 / Approved: 10 November 2021 / Online: 10 November 2021 (14:24:24 CET)
How to cite:
Lees, R.S.; Praulins, G.; Lissenden, N.; South, A.; Carson, J.; Brown, F.; Lucas, J.; Malone, D. The Residual Efficacy of SumiShield™ 50WG and K-Othrine® WG250 IRS Formulations Applied to Different Building Materials Against Anopheles and Aedes Mosquitoes. Preprints2021, 2021110206. https://doi.org/10.20944/preprints202111.0206.v1
Lees, R.S.; Praulins, G.; Lissenden, N.; South, A.; Carson, J.; Brown, F.; Lucas, J.; Malone, D. The Residual Efficacy of SumiShield™ 50WG and K-Othrine® WG250 IRS Formulations Applied to Different Building Materials Against Anopheles and Aedes Mosquitoes. Preprints 2021, 2021110206. https://doi.org/10.20944/preprints202111.0206.v1
Lees, R.S.; Praulins, G.; Lissenden, N.; South, A.; Carson, J.; Brown, F.; Lucas, J.; Malone, D. The Residual Efficacy of SumiShield™ 50WG and K-Othrine® WG250 IRS Formulations Applied to Different Building Materials Against Anopheles and Aedes Mosquitoes. Preprints2021, 2021110206. https://doi.org/10.20944/preprints202111.0206.v1
APA Style
Lees, R.S., Praulins, G., Lissenden, N., South, A., Carson, J., Brown, F., Lucas, J., & Malone, D. (2021). The Residual Efficacy of SumiShield™ 50WG and K-Othrine® WG250 IRS Formulations Applied to Different Building Materials Against Anopheles and Aedes Mosquitoes. Preprints. https://doi.org/10.20944/preprints202111.0206.v1
Chicago/Turabian Style
Lees, R.S., John Lucas and David Malone. 2021 "The Residual Efficacy of SumiShield™ 50WG and K-Othrine® WG250 IRS Formulations Applied to Different Building Materials Against Anopheles and Aedes Mosquitoes" Preprints. https://doi.org/10.20944/preprints202111.0206.v1
Abstract
Insecticides with novel modes of action are required to complement the pyrethroids currently relied upon for controlling malaria vectors. One example of this is the neonicotinoid clothianidin, which is found in SumiShield™ 50WG used in indoor residual spraying (IRS). In a preliminary experiment, mortality in insecticide susceptible and resistant An. gambiae adults exposed to SumiShield™ 50WG-treated filter papers reached 80% by 3-days post-exposure and 100% by 6-days post-exposure. Next, cement, wood, and mud tiles were treated with SumiShield™ 50WG or K-Othrine® WG250 (deltamethrin IRS formulation) and insecticide resistant and susceptible Anopheles and Aedes were exposed to these surfaces periodically for up to 18-months. Pyrethroid resistant Cx. quinquefasciatus were also exposed at 9 months. Between exposures tiles were stored in heat and relative humidity conditions reflecting those found in the field. On these surfaces, SumiShield™ 50WG was effective at killing both susceptible and resistant An. gambiae for 18 months post-treatment, while mortality amongst the resistant strains when exposed to deltamethrin (K-Othrine® WG250) IRS was not above that of the negative control. Greater efficacy of SumiShield™ 50WG was also demonstrated against insecticide resistant strains of An. funestus compared to deltamethrin, though the potency was lower when compared with An. gambiae. In general, a higher efficacy of SumiShield™ 50WG was observed on cement and mud compared to wood. SumiShield™ 50WG demonstrated poor residual activity against Aedes aegypti and Culex quinquefasciatus. Overall, the results suggest SumiShield™ 50WG is well suited for malaria control.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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