Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Sever Oligospermia Treatment with Testicular Sperm Using ICSI

Version 1 : Received: 25 September 2021 / Approved: 7 October 2021 / Online: 7 October 2021 (14:13:32 CEST)

How to cite: ZAKARIA, M.; AL-IBRAHEEMI, ,.A.; ENNAJI, M.; R.SENHAJI, W.; ZARQAOUI, M.; A.MOSSA, H.; MAMOUNE MBAYE, M.; LOUANJLI, N. Sever Oligospermia Treatment with Testicular Sperm Using ICSI. Preprints 2021, 2021100120 (doi: 10.20944/preprints202110.0120.v1). ZAKARIA, M.; AL-IBRAHEEMI, ,.A.; ENNAJI, M.; R.SENHAJI, W.; ZARQAOUI, M.; A.MOSSA, H.; MAMOUNE MBAYE, M.; LOUANJLI, N. Sever Oligospermia Treatment with Testicular Sperm Using ICSI. Preprints 2021, 2021100120 (doi: 10.20944/preprints202110.0120.v1).

Abstract

Assisted reproductive technology has been developed significantly throughout the past few years, particularly diagnosing and treating male infertility. Many studies have been performed showing that Intracytoplasmic Sperm Injection (ICSI) is a successful method to attain clinical pregnancy and live birth through impaired spermatozoa characteristics or low sperm count, such as severe oligospermia. Severe oligospermia indicates low sperm count, which in some cases leads to azoospermia. Severe oligospermia can be caused by several factors such as genetics or medication. In search of efficient treatment for couples with Severe oligospermia, numerous retrospective and prospective researches have reported high pregnancy and live birth rates through testicular sperm for men with severe oligospermia and cryptozoospermia with or without high sperm DNA damage. The research showed that the use of testicular sperm in combination with ICSI yielded a high pregnancy rate and live births over another source of sperm, such as ejaculated sperms. Moreover, the use of ICSI in severe oligospermia has shown successful fertilization and pregnancy.

Keywords

Sever oligospermia; Medication and cancer treatment influence on oligozoospermia; ICSI for men with sever oligozoospermia

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