Version 1
: Received: 20 September 2021 / Approved: 21 September 2021 / Online: 21 September 2021 (11:14:09 CEST)
How to cite:
Kohan Pour, M.; Aarabi, S.; Batouli, S.A.H.; Moallemian, S.; Oghabian, M.A. A Different Olfactory Perception in Anosmic Patients: Evidence from Functional MRI. Preprints2021, 2021090356. https://doi.org/10.20944/preprints202109.0356.v1
Kohan Pour, M.; Aarabi, S.; Batouli, S.A.H.; Moallemian, S.; Oghabian, M.A. A Different Olfactory Perception in Anosmic Patients: Evidence from Functional MRI. Preprints 2021, 2021090356. https://doi.org/10.20944/preprints202109.0356.v1
Kohan Pour, M.; Aarabi, S.; Batouli, S.A.H.; Moallemian, S.; Oghabian, M.A. A Different Olfactory Perception in Anosmic Patients: Evidence from Functional MRI. Preprints2021, 2021090356. https://doi.org/10.20944/preprints202109.0356.v1
APA Style
Kohan Pour, M., Aarabi, S., Batouli, S.A.H., Moallemian, S., & Oghabian, M.A. (2021). A Different Olfactory Perception in Anosmic Patients: Evidence from Functional MRI. Preprints. https://doi.org/10.20944/preprints202109.0356.v1
Chicago/Turabian Style
Kohan Pour, M., Soodeh Moallemian and Mohammad Ali Oghabian. 2021 "A Different Olfactory Perception in Anosmic Patients: Evidence from Functional MRI" Preprints. https://doi.org/10.20944/preprints202109.0356.v1
Abstract
Olfactory system is a vital sensory system in mammals, giving them the ability to connect with their environment. Anosmia, or the complete loss of olfaction ability, which could be caused by injuries, is an interesting topic for inspectors with the aim of diagnosing patients. Sniffing test is currently utilized to examine if an individual is suffering from anosmia; however, functional Magnetic Resonance Imaging (fMRI) provides unique information about the structure and function of the different areas of the human brain, and therefore this noninvasive method could be used as a tool to locate the olfactory-related regions of the brain. In this study, by recruiting 31 healthy and anosmic individuals, we investigated the neural BOLD responses in the olfactory cortices following two odor stimuli, rose and eucalyptus, by using a 3T MR scanner. Comparing the two groups, we observed a network of brain areas being more active in the normal individuals when smelling the odors. In addition, a number of brain areas also showed an activation decline during the odor stimuli, which is hypothesized as a resource allocation deactivation. This study illustrated alterations in the brain activity between the normal individuals and anosmic patients when smelling odors, and could potentially help for a better anosmia diagnosis in the future.
Keywords
Olfaction; functional MRI; Anosmia
Subject
Social Sciences, Behavior Sciences
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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