Submitted:
12 September 2021
Posted:
15 September 2021
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Abstract
Choanoflagellates, the closest living relatives of animals, have the potential to reveal the genetic and cell biological foundations of complex multicellular development in animals. Here we describe the history of research on the choanoflagellate Salpingoeca rosetta. From its original isolation in 2000 to the establishment of CRISPR-mediated genome editing in 2020, S. rosetta provides an instructive case study in the establishment of a new model organism.
Keywords:
choanoflagellates
; multicellularity
; animal origins
; genome editing
; electroporation
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